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    alpA DNA-binding transcriptional activator AlpA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946758, updated on 3-Dec-2024

    Summary

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    Official Symbol
    alpA
    Official Full Name
    DNA-binding transcriptional activator AlpA
    Primary source
    ECOCYC:EG12112
    Locus tag
    b2624
    See related
    ASAP:ABE-0008636
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2620
    Summary
    AlpA is a transcriptional regulator of intA expression . [More information is available at EcoCyc: EG12112].
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    Genomic context

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    Sequence:
    NC_000913.3 (2758644..2758856)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene integrase IntA Neighboring gene uncharacterized protein YfjH Neighboring gene DUF3987 domain-containing protein YfjI Neighboring gene protein YfjJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alp, a suppressor of lon protease mutants in Escherichia coli. Trempy JE, et al. J Bacteriol, 1989 Jun. PMID 2656652, Free PMC Article
    2. Excision of a P4-like cryptic prophage leads to Alp protease expression in Escherichia coli. Kirby JE, et al. J Bacteriol, 1994 Apr. PMID 7511583, Free PMC Article
    3. Analysis of the Escherichia coli Alp phenotype: heat shock induction in ssrA mutants. Munavar H, et al. J Bacteriol, 2005 Jul. PMID 15995188, Free PMC Article
    4. Genomic analysis of high-cell-density recombinant Escherichia coli fermentation and "cell conditioning" for improved recombinant protein yield. Gill RT, et al. Biotechnol Bioeng, 2001 Jan 5. PMID 11084598
    5. Prophages and bacterial genomics: what have we learned so far? Casjens S. Mol Microbiol, 2003 Jul. PMID 12886937

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within single-species biofilm formation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within single-species biofilm formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-binding transcriptional activator AlpA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2758644..2758856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417113.1 DNA-binding transcriptional activator AlpA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417113.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P33997
      Conserved Domains (1) summary
      COG3311
      Location:1 → 68
      AlpA; Predicted DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons]
    Nucleotide Protein
    Heading Accession and Version

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