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    frlA fructoselysine/psicoselysine transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947878, updated on 17-Dec-2024

    Summary

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    Official Symbol
    frlA
    Official Full Name
    fructoselysine/psicoselysine transporter
    Primary source
    ECOCYC:EG12908
    Locus tag
    b3370
    See related
    ASAP:ABE-0011019
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3358; yhfM
    Summary
    FrlA is an uncharacterized member of the APC superfamily of amino acid transporters . [More information is available at EcoCyc: EG12908].
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    Genomic context

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    Sequence:
    NC_000913.3 (3499910..3501247)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene siroheme synthase Neighboring gene DUF4223 domain-containing lipoprotein YhfL Neighboring gene fructoselysine 6-phosphate deglycase Neighboring gene fructoselysine 3-epimerase Neighboring gene fructoselysine 6-kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of glucoselysine-6-phosphate deglycase, an enzyme involved in the metabolism of the fructation product glucoselysine. Wiame E, et al. Biochem J, 2005 Dec 1. PMID 16153181, Free PMC Article
    2. Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli. Wiame E, et al. J Biol Chem, 2002 Nov 8. PMID 12147680
    3. Fructoselysine 3-epimerase, an enzyme involved in the metabolism of the unusual Amadori compound psicoselysine in Escherichia coli. Wiame E, et al. Biochem J, 2004 Mar 15. PMID 14641112, Free PMC Article
    4. The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations. Jack DL, et al. Microbiology (Reading), 2000 Aug. PMID 10931886
    5. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, et al. Science, 2005 May 27. PMID 15919996

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within fructoselysine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fructoselysine/psicoselysine transporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3499910..3501247
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417829.2 fructoselysine/psicoselysine transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417829.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1U9SVX0, A0A1X3JC60, A0A236GUN3, A0A2A2XEX8, A0A7I6H3I0, A0A9P2I7C3, A0AA35AM85, A0AAD2VBW8, A0AAD2ZDH2, A7ZSP6, J7QWL9
      Conserved Domains (1) summary
      PRK11357
      Location:1 → 445
      frlA; amino acid permease
    Nucleotide Protein
    Heading Accession and Version

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