U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    livF branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947961, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    livF
    Official Full Name
    branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF
    Primary source
    ECOCYC:EG10536
    Locus tag
    b3454
    See related
    ASAP:ABE-0011282
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3438
    Summary
    LivFGHMJ and LivFGHMK are two ATP-dependent high-affinity branched-chain amino acid transport system and are members of the ATP Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10536].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (3592724..3593437, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA Neighboring gene sn-glycerol 3-phosphate ABC transporter periplasmic binding protein Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport. Landick R, et al. J Biol Chem, 1985 Jul 15. PMID 3891753
    2. Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli. Nazos PM, et al. J Bacteriol, 1985 Sep. PMID 2993238, Free PMC Article
    3. Lrp, a leucine-responsive protein, regulates branched-chain amino acid transport genes in Escherichia coli. Haney SA, et al. J Bacteriol, 1992 Jan. PMID 1729203, Free PMC Article
    4. The LIV-I/LS system as a determinant of azaserine sensitivity of Escherichia coli K-12. Koyanagi T, et al. FEMS Microbiol Lett, 2004 Aug 1. PMID 15268940
    5. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-isoleucine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-leucine transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    contributes_to L-leucine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-valine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables branched-chain amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables branched-chain amino acid transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within L-valine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within branched-chain amino acid transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in branched-chain amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in branched-chain amino acid transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within isoleucine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within phenylalanine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phenylalanine transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF
    NP_417911.4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3592724..3593437 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417911.4 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417911.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1MQ44
      Conserved Domains (1) summary
      PRK11614
      Location:1 → 237
      livF; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.