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    yhiM inner membrane protein YhiM [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947997, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yhiM
    Official Full Name
    inner membrane protein YhiM
    Primary source
    ECOCYC:EG12228
    Locus tag
    b3491
    See related
    ASAP:ABE-0011400
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3476
    Summary
    EvgAS regulon. [More information is available at EcoGene: EG12228]. YhiM is an inner membrane protein with ten predicted membrane spanning domains; its C terminus is located in the cytoplasm . [More information is available at EcoCyc: EG12228].
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    Genomic context

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    Sequence:
    NC_000913.3 (3634841..3635893)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF4049 domain-containing protein YhiJ Neighboring gene pseudo Neighboring gene putative oxidoreductase YhiN Neighboring gene metal phosphate:H(+) symporter PitA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The inner membrane protein YhiM is necessary for Escherichia coli growth at high temperatures and low osmolarity. Anderson MA, et al. Arch Microbiol, 2017 Jan. PMID 27629277
    2. The inner membrane protein, YhiM, is necessary for Escherichia coli (E. coli) survival in acidic conditions. Nguyen TM, et al. Arch Microbiol, 2012 Jul. PMID 22327802
    3. Anticipating an alkaline stress through the Tor phosphorelay system in Escherichia coli. Bordi C, et al. Mol Microbiol, 2003 Apr. PMID 12657056
    4. Gene expression profiling of the pH response in Escherichia coli. Tucker DL, et al. J Bacteriol, 2002 Dec. PMID 12426343, Free PMC Article
    5. Low temperature (23 degrees C) increases expression of biofilm-, cold-shock- and RpoS-dependent genes in Escherichia coli K-12. White-Ziegler CA, et al. Microbiology (Reading), 2008 Jan. PMID 18174134

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. YhiM is important in protecting the cells from changes in temperature and osmolarity.
      Title: The inner membrane protein YhiM is necessary for Escherichia coli growth at high temperatures and low osmolarity.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to acidic pH IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to acidic pH IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in temperature homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inner membrane protein YhiM

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3634841..3635893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417948.4 inner membrane protein YhiM [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417948.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7L7EDW5, A0AAN3TS92
      Conserved Domains (1) summary
      pfam10951
      Location:1 → 348
      DUF2776; Protein of unknown function (DUF2776)
    Nucleotide Protein
    Heading Accession and Version

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