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    dctR putative DNA-binding transcriptional regulator DctR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948021, updated on 3-Dec-2024

    Summary

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    Official Symbol
    dctR
    Official Full Name
    putative DNA-binding transcriptional regulator DctR
    Primary source
    ECOCYC:EG11889
    Locus tag
    b3507
    See related
    ASAP:ABE-0011454
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3491; yhiF
    Summary
    DctR is in the EvgAS regulon. [More information is available at EcoGene: EG11889]. DctR is a predicted transcriptional regulator whose target may be dctA. [More information is available at EcoCyc: EG11889].
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    Genomic context

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    Sequence:
    NC_000913.3 (3654683..3655213)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene IS5 family transposase and trans-activator Neighboring gene starvation lipoprotein Neighboring gene inner membrane protein YhiD Neighboring gene periplasmic acid stress chaperone HdeB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DctR contributes to the virulence of avian pathogenic Escherichia coli through regulation of type III secretion system 2 expression. Zhang Y, et al. Vet Res, 2021 Jul 6. PMID 34229767, Free PMC Article
    2. Increased adherence to Caco-2 cells caused by disruption of the yhiE and yhiF genes in enterohemorrhagic Escherichia coli O157:H7. Tatsuno I, et al. Infect Immun, 2003 May. PMID 12704134, Free PMC Article
    3. GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli. Hommais F, et al. Microbiology (Reading), 2004 Jan. PMID 14702398
    4. atp Mutants of Escherichia coli fail to grow on succinate due to a transport deficiency. Boogerd FC, et al. J Bacteriol, 1998 Nov. PMID 9811641, Free PMC Article
    5. Products of the Escherichia coli acid fitness island attenuate metabolite stress at extremely low pH and mediate a cell density-dependent acid resistance. Mates AK, et al. J Bacteriol, 2007 Apr. PMID 17259322, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DctR contributes to the virulence of avian pathogenic Escherichia coli through regulation of type III secretion system 2 expression.
      Title: DctR contributes to the virulence of avian pathogenic Escherichia coli through regulation of type III secretion system 2 expression.
    2. RcsB forms heterodimers with MatA (also known as EcpR) and with DctR
      Title: Interaction of the RcsB Response Regulator with Auxiliary Transcription Regulators in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular stress response to acidic pH IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative DNA-binding transcriptional regulator DctR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3654683..3655213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417964.1 putative DNA-binding transcriptional regulator DctR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417964.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7KD89
      Conserved Domains (2) summary
      smart00421
      Location:113 → 169
      HTH_LUXR; helix_turn_helix, Lux Regulon
      COG2197
      Location:2 → 168
      CitB; DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription]
    Nucleotide Protein
    Heading Accession and Version

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