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    ulaC L-ascorbate specific PTS enzyme IIA component [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948715, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ulaC
    Official Full Name
    L-ascorbate specific PTS enzyme IIA component
    Primary source
    ECOCYC:EG12495
    Locus tag
    b4195
    See related
    ASAP:ABE-0013727
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4191; ptxA; sgaA; yjfU
    Summary
    The ula divergon is comprised of the two divergent ulaGR and ulaABCDEF operons. [More information is available at EcoGene: EG12495]. UlaC: "utilization of L-ascorbate" . [More information is available at EcoCyc: EG12495].
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    Genomic context

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    Sequence:
    NC_000913.3 (4421708..4422172)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-ascorbate specific PTS enzyme IIC component Neighboring gene L-ascorbate specific PTS enzyme IIB component Neighboring gene 3-keto-L-gulonate-6-phosphate decarboxylase UlaD Neighboring gene L-ribulose-5-phosphate 3-epimerase UlaE Neighboring gene L-ribulose-5-phosphate 4-epimerase UlaF

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Investigation into the resistance of lactoperoxidase tolerant Escherichia coli mutants to different forms of oxidative stress. De Spiegeleer P, et al. FEMS Microbiol Lett, 2005 Nov 15. PMID 16209909
    2. Bioinformatic analyses of the bacterial L-ascorbate phosphotransferase system permease family. Hvorup R, et al. J Mol Microbiol Biotechnol, 2003. PMID 15153772
    3. Is the ribulose monophosphate pathway widely distributed in bacteria? Reizer J, et al. Microbiology (Reading), 1997 Aug. PMID 9274005
    4. The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli. Campos E, et al. J Bacteriol, 2002 Nov. PMID 12374842, Free PMC Article
    5. The ascorbate transporter of Escherichia coli. Zhang Z, et al. J Bacteriol, 2003 Apr. PMID 12644495, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-ascorbic acid transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in L-ascorbic acid transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transmembrane transporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    L-ascorbate specific PTS enzyme IIA component
    NP_418616.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4421708..4422172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418616.1 L-ascorbate specific PTS enzyme IIA component [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418616.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A830V2N9
      Conserved Domains (1) summary
      PRK10372
      Location:1 → 154
      PRK10372; PTS ascorbate transporter subunit IIA
    Nucleotide Protein
    Heading Accession and Version

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