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    paeA putative cadaverine/putrescine exporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948735, updated on 3-Dec-2024

    Summary

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    Official Symbol
    paeA
    Official Full Name
    putative cadaverine/putrescine exporter
    Primary source
    ECOCYC:G7873
    Locus tag
    b4218
    See related
    ASAP:ABE-0013799
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4214; ytfL
    Summary
    YtfL is an inner membrane protein with 4 predicted transmembrane helices. [More information is available at EcoCyc: G7873].
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    Genomic context

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    Sequence:
    NC_000913.3 (4439872..4441215, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF09695 family protein YtfJ Neighboring gene stringent response modulator YtfK Neighboring gene methionine sulfoxide reductase A Neighboring gene translocation and assembly module subunit TamA Neighboring gene translocation and assembly module subunit TamB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PaeA (YtfL) protects from cadaverine and putrescine stress in Salmonella Typhimurium and E. coli. Iwadate Y, et al. Mol Microbiol, 2021 Jun. PMID 33481283, Free PMC Article
    2. Global analysis of candidate genes important for fitness in a competitive biofilm using DNA-array-based transposon mapping. Junker LM, et al. Microbiology (Reading), 2006 Aug. PMID 16849790
    3. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Zhang N, et al. Proteomics, 2007 Feb. PMID 17309111
    4. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article
    5. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PaeA (YtfL) protects from cadaverine and putrescine stress in Salmonella Typhimurium and E. coli.
      Title: PaeA (YtfL) protects from cadaverine and putrescine stress in Salmonella Typhimurium and E. coli.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative cadaverine/putrescine exporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4439872..4441215 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418639.1 putative cadaverine/putrescine exporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418639.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AN64
      Conserved Domains (1) summary
      COG1253
      Location:1 → 428
      TlyC; Hemolysin or related protein, contains CBS domains [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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