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    coaE dephospho-CoA kinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949060, updated on 3-Dec-2024

    Summary

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    Official Symbol
    coaE
    Official Full Name
    dephospho-CoA kinase
    Primary source
    ECOCYC:EG12312
    Locus tag
    b0103
    See related
    ASAP:ABE-0000357
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0103; yacE
    Summary
    coaE is essential for growth as tested by genetic footprinting. [More information is available at EcoGene: EG12312]. Dephospho-CoA kinase catalyzes the final step in coenzyme A biosynthesis . [More information is available at EcoCyc: EG12312].
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    Genomic context

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    Sequence:
    NC_000913.3 (112599..113219, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA gyrase inhibitor YacG Neighboring gene cell division factor ZapD Neighboring gene protein YacM Neighboring gene GMP reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of a trimeric form of dephosphocoenzyme A kinase from Escherichia coli. O'Toole N, et al. Protein Sci, 2003 Feb. PMID 12538896, Free PMC Article
    2. Activity-based substrate profiling for Gcn5-related N-acetyltransferases: the use of chloroacetyl-coenzyme A to identify protein substrates. Yu M, et al. J Am Chem Soc, 2006 Dec 6. PMID 17131985, Free PMC Article
    3. Identification of yacE (coaE) as the structural gene for dephosphocoenzyme A kinase in Escherichia coli K-12. Mishra P, et al. J Bacteriol, 2001 May. PMID 11292795, Free PMC Article
    4. Genetic footprinting in bacteria. Hare RS, et al. J Bacteriol, 2001 Mar. PMID 11160101, Free PMC Article
    5. Structural analysis of a set of proteins resulting from a bacterial genomics project. Badger J, et al. Proteins, 2005 Sep 1. PMID 16021622

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dephospho-CoA kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dephospho-CoA kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dephospho-CoA kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in coenzyme A biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within coenzyme A biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in coenzyme A biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dephospho-CoA kinase
    NP_414645.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      112599..113219 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414645.1 dephospho-CoA kinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414645.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376ME76, A0A8T6Q544
      Conserved Domains (1) summary
      PRK00081
      Location:1 → 193
      coaE; dephospho-CoA kinase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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