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    ampH peptidoglycan DD-carboxypeptidase/peptidoglycan DD-endopeptidase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946904, updated on 3-Dec-2024

    Summary

    Official Symbol
    ampH
    Official Full Name
    peptidoglycan DD-carboxypeptidase/peptidoglycan DD-endopeptidase
    Primary source
    ECOCYC:EG12867
    Locus tag
    b0376
    See related
    ASAP:ABE-0001292
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0371; yaiH
    Summary
    AmpH is a penicillin-binding protein with no known enzymatic function. [More information is available at EcoCyc: EG12867].
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    Genomic context

    Sequence:
    NC_000913.3 (395130..396287, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene IS3 element protein InsF Neighboring gene IS3 element protein InsE Neighboring gene putative DNA-binding transcriptional regulator IprA Neighboring gene peptide antibiotic/peptide nucleic acid transporter Neighboring gene surface-exposed outer membrane lipoprotein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carboxypeptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables carboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables penicillin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidoglycan catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell shape IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    peptidoglycan DD-carboxypeptidase/peptidoglycan DD-endopeptidase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      395130..396287 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414910.1 peptidoglycan DD-carboxypeptidase/peptidoglycan DD-endopeptidase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414910.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FRN3
      Conserved Domains (1) summary
      PRK10662
      Location:1378
      PRK10662; beta-lactam binding protein AmpH; Provisional