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    allR DNA-binding transcriptional repressor AllR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945333, updated on 3-Dec-2024

    Summary

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    Official Symbol
    allR
    Official Full Name
    DNA-binding transcriptional repressor AllR
    Primary source
    ECOCYC:G6276
    Locus tag
    b0506
    See related
    ASAP:ABE-0001750
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0499; glxA3; ybbU
    Summary
    IclR family. [More information is available at EcoGene: EG13616].
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    Genomic context

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    Sequence:
    NC_000913.3 (533011..533826)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator AllS Neighboring gene ureidoglycolate lyase Neighboring gene ncRNA Neighboring gene glyoxylate carboligase Neighboring gene hydroxypyruvate isomerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and biochemical study of effector molecule recognition by the E.coli glyoxylate and allantoin utilization regulatory protein AllR. Walker JR, et al. J Mol Biol, 2006 May 5. PMID 16546208
    2. Mass spectrometric study of the Escherichia coli repressor proteins, Ic1R and Gc1R, and their complexes with DNA. Donald LJ, et al. Protein Sci, 2001 Jul. PMID 11420439, Free PMC Article
    3. The transcription regulator AllR senses both allantoin and glyoxylate and controls a set of genes for degradation and reutilization of purines. Hasegawa A, et al. Microbiology (Reading), 2008 Nov. PMID 18957590
    4. Regulation of the Escherichia coli allantoin regulon: coordinated function of the repressor AllR and the activator AllS. Rintoul MR, et al. J Mol Biol, 2002 Dec 6. PMID 12460564
    5. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AllR, together with AllS, plays a key role in switching control of two pathways, nitrogen assimilation and energy production.
      Title: The transcription regulator AllR senses both allantoin and glyoxylate and controls a set of genes for degradation and reutilization of purines.
    2. glyoxylate was shown to conformationally change the AllR tetramer as well as monomer and dimer resulting in altered outline of AllR molecules
      Title: Structural and biochemical study of effector molecule recognition by the E.coli glyoxylate and allantoin utilization regulatory protein AllR.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-binding transcriptional repressor AllR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      533011..533826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415039.1 DNA-binding transcriptional repressor AllR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415039.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9QDQ8
      Conserved Domains (1) summary
      PRK10163
      Location:1 → 271
      PRK10163; HTH-type transcriptional repressor AllR
    Nucleotide Protein
    Heading Accession and Version

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