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    hspQ heat shock protein HspQ [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945578, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hspQ
    Official Full Name
    heat shock protein HspQ
    Primary source
    ECOCYC:G6500
    Locus tag
    b0966
    See related
    ASAP:ABE-0003269
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0957; yccV
    Summary
    A mutation in hspQ allows some dnaA(Ts) strains to grow at 40C, and slows the degradation of DnaA508 at 40C. [More information is available at EcoGene: EG13724]. HspQ binds to hemimethylated DNA at oriC . [More information is available at EcoCyc: G6500].
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    Genomic context

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    Sequence:
    NC_000913.3 (1028404..1028721, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2057 domain-containing protein YccT Neighboring gene putative HspQ acetyl donor Neighboring gene 23S rRNA m(5)C1962 methyltransferase Neighboring gene acylphosphatase Neighboring gene sulfur transfer protein TusE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation. Abe Y, et al. FEBS Lett, 2017 Nov. PMID 29083032
    2. The global transcriptional response of Escherichia coli to induced sigma 32 protein involves sigma 32 regulon activation followed by inactivation and degradation of sigma 32 in vivo. Zhao K, et al. J Biol Chem, 2005 May 6. PMID 15757896
    3. Novel heat shock protein HspQ stimulates the degradation of mutant DnaA protein in Escherichia coli. Shimuta TR, et al. Genes Cells, 2004 Dec. PMID 15569148
    4. Isolation of a new hemimethylated DNA binding protein which regulates dnaA gene expression. d'Alençon E, et al. J Bacteriol, 2003 May. PMID 12700277, Free PMC Article
    5. Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress. Nonaka G, et al. Genes Dev, 2006 Jul 1. PMID 16818608, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Novel heat shock protein HspQ stimulates the degradation of mutant DnaA protein in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hemi-methylated DNA-binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein homotrimerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to heat IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    heat shock protein HspQ

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1028404..1028721 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415486.4 heat shock protein HspQ [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415486.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A484WQQ4
      Conserved Domains (1) summary
      PRK14129
      Location:1 → 105
      PRK14129; heat shock protein HspQ; Provisional
    Nucleotide Protein
    Heading Accession and Version

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