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    sgbE L-ribulose-5-phosphate 4-epimerase SgbE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948099, updated on 17-Dec-2024

    Summary

    Official Symbol
    sgbE
    Official Full Name
    L-ribulose-5-phosphate 4-epimerase SgbE
    Primary source
    ECOCYC:EG12287
    Locus tag
    b3583
    See related
    ASAP:ABE-0011702
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3572; yiaS
    Summary
    YiaQ is possibly involved in the utilization of L-dehydroascorbate (2,3-diketo-L-gulonate) (Yew, 2002). [More information is available at EcoGene: EG12287]. The sgbE gene encodes a second L-ribulose-5-phosphate 4-epimerase that functions in metabolism of L-lyxose and L-xylulose . [More information is available at EcoCyc: EG12287].
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    Genomic context

    Sequence:
    NC_000913.3 (3750086..3750781)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein Neighboring gene L-xylulose kinase Neighboring gene 3-keto-L-gulonate-6-phosphate decarboxylase SgbH Neighboring gene putative L-xylulose 5-phosphate 3-epimerase Neighboring gene pseudo Neighboring gene pseudo

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-ribulose-phosphate 4-epimerase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables L-ribulose-phosphate 4-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables aldehyde-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in L-arabinose catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within L-lyxose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in monosaccharide metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pentose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within pentose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    L-ribulose-5-phosphate 4-epimerase SgbE
    NP_418040.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3750086..3750781
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418040.1 L-ribulose-5-phosphate 4-epimerase SgbE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418040.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A776QVQ5
      Conserved Domains (1) summary
      PRK12347
      Location:1231
      sgbE; L-ribulose-5-phosphate 4-epimerase; Reviewed