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    dgoK 2-dehydro-3-deoxygalactonokinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948207, updated on 17-Dec-2024

    Summary

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    Official Symbol
    dgoK
    Official Full Name
    2-dehydro-3-deoxygalactonokinase
    Primary source
    ECOCYC:EG20051
    Locus tag
    b3693
    See related
    ASAP:ABE-0012076
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3686; yidV
    Summary
    2-dehydro-3-deoxygalactonate kinase catalyzes the second reaction in the degradation of D-galactonate, the ATP-dependent phosphorylation of 2-dehydro-3-deoxygalactonate . [More information is available at EcoCyc: EG20051].
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    Genomic context

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    Sequence:
    NC_000913.3 (3873596..3874474, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene colicin M resistance protein Neighboring gene D-galactonate:H(+) symporter Neighboring gene D-galactonate dehydratase Neighboring gene 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Neighboring gene DNA-binding transcriptional regulator DgoR Neighboring gene putative lipoprotein YidX Neighboring gene sugar phosphatase YidA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids. Babbitt PC, et al. Science, 1995 Feb 24. PMID 7855594
    2. Identification of genes affecting lycopene accumulation in Escherichia coli using a shot-gun method. Kang MJ, et al. Biotechnol Bioeng, 2005 Sep 5. PMID 15898075
    3. The utilisation of D-galactonate and D-2-oxo-3-deoxygalactonate by Escherichia coli K-12. Biochemical and genetical studies. Cooper RA. Arch Microbiol, 1978 Aug 1. PMID 211976
    4. D-Galactonate utilisation by enteric bacteria. The catabolic pathway in Escherichia coli. Deacon J, et al. FEBS Lett, 1977 May 15. PMID 324806
    5. Molecular and Functional Insights into the Regulation of d-Galactonate Metabolism by the Transcriptional Regulator DgoR in Escherichia coli. Singh B, et al. J Bacteriol, 2019 Feb 15. PMID 30455279, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2-dehydro-3-deoxygalactonokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 2-dehydro-3-deoxygalactonokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-galactonate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within D-galactonate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in carbohydrate phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    2-dehydro-3-deoxygalactonokinase
    NP_418148.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3873596..3874474 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418148.1 2-dehydro-3-deoxygalactonokinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418148.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FXG9
      Conserved Domains (1) summary
      COG3734
      Location:3 → 292
      DgoK; 2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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