asnA asparagine synthetase A [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: asnA
Official Full Name: asparagine synthetase A
Primary source: ECOCYC:EG10091
Locus tag: b3744
See related: ASAP:ABE-0012242
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK3738
Summary: AsnA and AsnB are redundant; an asparagine auxotrophy requires that both genes be mutated. [More information is available at EcoGene: EG10091]. Asparagine synthetase A (AsnA) is one of two asparagine synthetases in Escherichia coli, catalyzing the ammonia-dependent conversion of aspartate to asparagine. [More information is available at EcoCyc: EG10091].
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NC_000913.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables aspartate-ammonia ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables aspartate-ammonia ligase activity	IDA Inferred from Direct Assay more info	PubMed
enables aspartate-ammonia ligase activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IEP Inferred from Expression Pattern more info	PubMed
involved_in L-asparagine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in asparagine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in asparagine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within asparagine biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

NP_418200.1

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The following sections contain reference sequences that belong to a specific genome build. Explain