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    cdh CDP-diacylglycerol diphosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948410, updated on 3-Dec-2024

    Summary

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    Official Symbol
    cdh
    Official Full Name
    CDP-diacylglycerol diphosphatase
    Primary source
    ECOCYC:EG10138
    Locus tag
    b3918
    See related
    ASAP:ABE-0012797
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3910
    Summary
    It is unclear if Cdh(E.c.) has UshB or PnuE activity. [More information is available at EcoGene: EG10138].
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    Genomic context

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    Sequence:
    NC_000913.3 (4109930..4110685)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 6-phosphofructokinase 1 Neighboring gene sulfate/thiosulfate ABC transporter periplasmic binding protein Sbp Neighboring gene triose-phosphate isomerase Neighboring gene DUF1454 domain-containing protein YiiQ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Partial purification and characterization of cytidine 5'-diphosphate-diglyceride hydrolase from membranes of Escherichia coli. Raetz CR, et al. J Bacteriol, 1976 Mar. PMID 1254556, Free PMC Article
    2. A membrane-bound pyrophosphatase in Escherichia coli catalyzing the hydrolysis of cytidine diphosphate-diglyceride. Raetz CR, et al. J Biol Chem, 1972 Apr 10. PMID 4335869
    3. Enzymatic sorting of bacterial colonies on filter paper replicas: detection of labile activities. Bulawa CE, et al. J Bacteriol, 1981 Oct. PMID 6116698, Free PMC Article
    4. Isolation and characterization of Escherichia coli strains defective in CDP-diglyceride hydrolase. Bulawa CE, et al. J Biol Chem, 1984 Sep 25. PMID 6147353
    5. The Escherichia coli orthologue of the Salmonella ushB gene (ushB(c)) produces neither UDP-sugar hydrolase activity nor detectable protein, but has an identical sequence to that of Escherichia coli cdh. Schroder W, et al. FEMS Microbiol Lett, 2001 Sep 11. PMID 11557141

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables CDP-diacylglycerol diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables CDP-diacylglycerol diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in CDP-diacylglycerol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within CDP-diacylglycerol catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CDP-diacylglycerol diphosphatase
    NP_418353.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4109930..4110685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418353.1 CDP-diacylglycerol diphosphatase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418353.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AMA2
      Conserved Domains (1) summary
      TIGR00672
      Location:1 → 251
      cdh; CDP-diacylglycerol diphosphatase, bacterial type
    Nucleotide Protein
    Heading Accession and Version

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