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    rimK ribosomal protein S6 modification protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945484, updated on 17-Dec-2024

    Summary

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    Official Symbol
    rimK
    Official Full Name
    ribosomal protein S6 modification protein
    Primary source
    ECOCYC:EG10852
    Locus tag
    b0852
    See related
    ASAP:ABE-0002903
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0843; nek
    Summary
    RimK is required for wild-type post-translational addition of C-terminal glutamic acid residues to ribosomal protein S6 (RpsF) . [More information is available at EcoCyc: EG10852].
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    Genomic context

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    Sequence:
    NC_000913.3 (891967..892869)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene reduced glutaredoxin 1 Neighboring gene DUF1418 domain-containing protein YbjC Neighboring gene NADPH-dependent nitro/quinone reductase NfsA Neighboring gene protein YbjN Neighboring gene putrescine ABC transporter periplasmic binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Poly-alpha-glutamic acid synthesis using a novel catalytic activity of RimK from Escherichia coli K-12. Kino K, et al. Appl Environ Microbiol, 2011 Mar. PMID 21278279, Free PMC Article
    2. Coresistance to neomycin and kanamycin by mutations in an Escherichia coli locus that affects ribosomes. Apirion D, et al. J Bacteriol, 1968 Sep. PMID 4895052, Free PMC Article
    3. Isolation and characterization of mutants of Escherichia coli K12 resistant to the new aminoglycoside antibiotic, amikacin. Hull R, et al. J Gen Microbiol, 1976 Jun. PMID 781182
    4. Oligoglutamylation of E. coli ribosomal protein S6 is under growth phase control. Pletnev PI, et al. Biochimie, 2019 Dec. PMID 31520657
    5. Genome-wide screening with hydroxyurea reveals a link between nonessential ribosomal proteins and reactive oxygen species production. Nakayashiki T, et al. J Bacteriol, 2013 Mar. PMID 23292777, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. S6 modification is regulated solely via the rate of ribosome biosynthesis at limiting concentration of RimK enzyme.
      Title: Oligoglutamylation of E. coli ribosomal protein S6 is under growth phase control.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosomal S6-glutamic acid ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribosomal S6-glutamic acid ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ribosomal S6-glutamic acid ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in SOS response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within SOS response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein modification process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein S6 modification protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      891967..892869
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415373.1 ribosomal protein S6 modification protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415373.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7ECI2, A0A8S7X4W2, A0AAE9PWQ0
      Conserved Domains (1) summary
      PRK10446
      Location:1 → 300
      PRK10446; 30S ribosomal protein S6--L-glutamate ligase
    Nucleotide Protein
    Heading Accession and Version

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