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    gstA glutathione S-transferase GstA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945758, updated on 17-Dec-2024

    Summary

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    Official Symbol
    gstA
    Official Full Name
    glutathione S-transferase GstA
    Primary source
    ECOCYC:G6878
    Locus tag
    b1635
    See related
    ASAP:ABE-0005473
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1631; gst
    Summary
    Glutathione S-transferase acts as a detoxifying enzyme. [More information is available at EcoCyc: G6878].
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    Genomic context

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    Sequence:
    NC_000913.3 (1714377..1714982)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene SoxR [2Fe-2S] reducing system protein RsxE Neighboring gene endonuclease III Neighboring gene dipeptide/tripeptide:H(+) symporter DtpA Neighboring gene pyridoxal kinase 2 Neighboring gene tyrosine--tRNA ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the activity and folding of the glutathione transferase from Escherichia coli and the roles of residues Cys(10) and His(106). Wang XY, et al. Biochem J, 2009 Jan 1. PMID 18778244
    2. Chlorothalonil-biotransformation by glutathione S-transferase of Escherichia coli. Kim YM, et al. J Microbiol, 2004 Mar. PMID 15357291
    3. Molecular cloning and site-directed mutagenesis of glutathione S-transferase from Escherichia coli. The conserved tyrosyl residue near the N terminus is not essential for catalysis. Nishida M, et al. J Biol Chem, 1994 Dec 23. PMID 7798255
    4. Purification and some properties of glutathione S-transferase from Escherichia coli B. Iizuka M, et al. J Bacteriol, 1989 Nov. PMID 2553668, Free PMC Article
    5. Purification and study of a bacterial glutathione S-transferase. Arca P, et al. FEBS Lett, 1990 Apr 9. PMID 2185038

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Molecular cloning and site-directed mutagenesis of glutathione S-transferase from Escherichia coli. The conserved tyrosyl residue near the N terminus is not essential for catalysis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to hydrogen peroxide IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glutathione S-transferase GstA
    NP_416152.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1714377..1714982
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416152.1 glutathione S-transferase GstA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416152.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7R3X4
      Conserved Domains (1) summary
      PRK10542
      Location:1 → 201
      PRK10542; glutathionine S-transferase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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