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    yehX glycine betaine ABC transporter ATP binding subunit YehX [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946659, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yehX
    Official Full Name
    glycine betaine ABC transporter ATP binding subunit YehX
    Primary source
    ECOCYC:EG12010
    Locus tag
    b2129
    See related
    ASAP:ABE-0007034
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2122
    Summary
    RpoS regulon. [More information is available at EcoGene: EG12010]. YehX is the ATP-binding component of an ABC transporter involved in osmoprotection. [More information is available at EcoCyc: EG12010].
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    Genomic context

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    Sequence:
    NC_000913.3 (2216481..2217407, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator MlrA Neighboring gene UPF0387 family protein YohO Neighboring gene glycine betaine ABC transporter membrane subunit YehW Neighboring gene glycine betaine ABC transporter membrane subunit YehY Neighboring gene glycine betaine ABC transporter periplasmic binding protein OsmF Neighboring gene beta-D-glucoside glucohydrolase, periplasmic

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Osmoregulatory systems of Escherichia coli: identification of betaine-carnitine-choline transporter family member BetU and distributions of betU and trkG among pathogenic and nonpathogenic isolates. Ly A, et al. J Bacteriol, 2004 Jan. PMID 14702297, Free PMC Article
    2. YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter. Lang S, et al. Biochemistry, 2015 Sep 22. PMID 26325238
    3. The Escherichia coli ATP-binding cassette (ABC) proteins. Linton KJ, et al. Mol Microbiol, 1998 Apr. PMID 9593292
    4. Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters. Saurin W, et al. J Mol Evol, 1999 Jan. PMID 9873074
    5. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ABC-type glycine betaine transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ABC-type glycine betaine transporter activity RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino-acid betaine transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within glycine betaine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine betaine ABC transporter ATP binding subunit YehX

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2216481..2217407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416633.1 glycine betaine ABC transporter ATP binding subunit YehX [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416633.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A403D6D4
      Conserved Domains (1) summary
      COG1125
      Location:1 → 308
      OpuBA; ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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