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    hycF formate hydrogenlyase subunit HycF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947048, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hycF
    Official Full Name
    formate hydrogenlyase subunit HycF
    Primary source
    ECOCYC:EG10479
    Locus tag
    b2720
    See related
    ASAP:ABE-0008942
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2715; hevF
    Summary
    FhlA regulon. [More information is available at EcoGene: EG10479]. HycF is thought to encode a 4Fe-4S ferredoxin type protein, an intermediate electron carrier protein . [More information is available at EcoCyc: EG10479].
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    Genomic context

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    Sequence:
    NC_000913.3 (2844210..2844752, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 6-phospho-beta-glucosidase AscB Neighboring gene hydrogenase 3 maturation protease Neighboring gene formate hydrogenlyase assembly protein Neighboring gene formate hydrogenlyase subunit HycG Neighboring gene formate hydrogenlyase subunit HycE Neighboring gene formate hydrogenlyase subunit HycD

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microbial reduction of technetium by Escherichia coli and Desulfovibrio desulfuricans: enhancement via the use of high-activity strains and effect of process parameters. Lloyd JR, et al. Biotechnol Bioeng, 1999. PMID 10567070
    2. Reduction and removal of heptavalent technetium from solution by Escherichia coli. Lloyd JR, et al. J Bacteriol, 1997 Mar. PMID 9068649, Free PMC Article
    3. Regulation of gene expression in fermentative and respiratory systems in Escherichia coli and related bacteria. Lin EC, et al. Annu Rev Genet, 1991. PMID 1812811
    4. Regulated expression in vitro of genes coding for formate hydrogenlyase components of Escherichia coli. Hopper S, et al. J Biol Chem, 1994 Jul 29. PMID 8034728
    5. The hydrogenases and formate dehydrogenases of Escherichia coli. Sawers G. Antonie Van Leeuwenhoek, 1994. PMID 7747941

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 4 iron, 4 sulfur cluster binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    contributes_to NADH dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on NAD(P)H IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in aerobic respiration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in anaerobic electron transport chain IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in anaerobic respiration IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in formate oxidation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glucose catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of formate dehydrogenase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    formate hydrogenlyase subunit HycF
    NP_417200.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2844210..2844752 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417200.1 formate hydrogenlyase subunit HycF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417200.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6L7CE10
      Conserved Domains (1) summary
      PRK12387
      Location:1 → 180
      PRK12387; formate hydrogenlyase complex iron-sulfur subunit; Provisional
    Nucleotide Protein
    Heading Accession and Version

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