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    rtcR DNA-binding transcriptional activator RtcR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947928, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rtcR
    Official Full Name
    DNA-binding transcriptional activator RtcR
    Primary source
    ECOCYC:EG12356
    Locus tag
    b3422
    See related
    ASAP:ABE-0011174
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3408; yhgB
    Summary
    RtcR , "RNA terminal phosphate cyclase regulator," regulates the expression of genes involved in the ATP-dependent conversion of a 3'-phosphate at the end of RNA to 2',3'-cyclic phosphodiester . [More information is available at EcoCyc: EG12356].
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    Genomic context

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    Sequence:
    NC_000913.3 (3558268..3559866)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene RNA-splicing ligase Neighboring gene pseudo Neighboring gene rhomboid protease GlpG Neighboring gene thiosulfate sulfurtransferase GlpE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large scale bacterial gene discovery by similarity search. Robison K, et al. Nat Genet, 1994 Jun. PMID 7920643
    2. Nucleotide sequence of the glpR gene encoding the repressor for the glycerol-3-phosphate regulon of Escherichia coli K12. Choi YL, et al. Nucleic Acids Res, 1988 Aug 11. PMID 3045764, Free PMC Article
    3. Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon. Genschik P, et al. J Biol Chem, 1998 Sep 25. PMID 9738023
    4. Intrinsic and extrinsic approaches for detecting genes in a bacterial genome. Borodovsky M, et al. Nucleic Acids Res, 1994 Nov 11. PMID 7984428, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphorelay signal transduction system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-DNA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional activator RtcR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3558268..3559866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417880.1 DNA-binding transcriptional activator RtcR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417880.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1V2GIB7
      Conserved Domains (1) summary
      COG4650
      Location:1 → 531
      RtcR; Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

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