U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ahr NADPH-dependent aldehyde reductase Ahr [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948802, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ahr
    Official Full Name
    NADPH-dependent aldehyde reductase Ahr
    Primary source
    ECOCYC:EG11436
    Locus tag
    b4269
    See related
    ASAP:ABE-0013982
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4262; yjgB
    Summary
    Salmonella ortholog regulated by RpoS. [More information is available at EcoGene: EG11436]. The yjgB gene of Salmonella enterica serovar Typhimurium is part of the RpoS regulon . [More information is available at EcoCyc: EG11436].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4495190..4496209, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-idonate 5-dehydrogenase Neighboring gene D-gluconate kinase, thermosensitive Neighboring gene tRNA-Leu Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural Basis for Broad Substrate Selectivity of Alcohol Dehydrogenase YjgB from Escherichia coli. Nguyen GT, et al. Molecules, 2020 May 21. PMID 32455802, Free PMC Article
    2. Isobutyraldehyde production from Escherichia coli by removing aldehyde reductase activity. Rodriguez GM, et al. Microb Cell Fact, 2012 Jun 25. PMID 22731523, Free PMC Article
    3. Exploring the microbial metalloproteome using MIRAGE. Sevcenco AM, et al. Metallomics, 2011 Dec. PMID 22094925
    4. Identification of RpoS (sigma(S))-regulated genes in Salmonella enterica serovar typhimurium. Ibanez-Ruiz M, et al. J Bacteriol, 2000 Oct. PMID 11004173, Free PMC Article
    5. Novel CAD-like enzymes from Escherichia coli K-12 as additional tools in chemical production. Pick A, et al. Appl Microbiol Biotechnol, 2013 Jul. PMID 23093176, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Structural Basis for Broad Substrate Selectivity of Alcohol Dehydrogenase YjgB from Escherichia coli.
      Title: Structural Basis for Broad Substrate Selectivity of Alcohol Dehydrogenase YjgB from Escherichia coli.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables alcohol dehydrogenase (NADP+) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables alcohol dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    NADPH-dependent aldehyde reductase Ahr
    NP_418690.4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4495190..4496209 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418690.4 NADPH-dependent aldehyde reductase Ahr [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418690.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EFD4
      Conserved Domains (1) summary
      cd05283
      Location:5 → 336
      CAD1; Cinnamyl alcohol dehydrogenases (CAD)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.