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    deoB phosphopentomutase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948910, updated on 3-Dec-2024

    Summary

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    Official Symbol
    deoB
    Official Full Name
    phosphopentomutase
    Primary source
    ECOCYC:EG10220
    Locus tag
    b4383
    See related
    ASAP:ABE-0014377
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    drm; ECK4375; thyR; tlr
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    Genomic context

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    Sequence:
    NC_000913.3 (4619603..4620826)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene deoxyribose-phosphate aldolase Neighboring gene thymidine phosphorylase Neighboring gene purine nucleoside phosphorylase Neighboring gene toxin YjjJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple forms of phosphodeoxyribomutase from Escherichia coli. Physical and chemical characterization. Leer JC, et al. Biochemistry, 1975 Feb 11. PMID 1089430
    2. Phosphodeoxyribomutase from Escherichia coli. Purification and some properties. Hammer-Jespersen K, et al. Eur J Biochem, 1970 Dec. PMID 4992818
    3. Thymineless mutants of Escherichia coli with deficiencies in deoxyribomutase and deoxyriboaldolase. Munch-Petersen A. Biochim Biophys Acta, 1968 Jun 18. PMID 4873559
    4. Inability of low thymine-requiring mutants of Escherichia coli lacking phosphodeoxyribomutase to be induced for deoxythymidine phosphorylase and deoxyriboaldolase. Breitman TR, et al. J Bacteriol, 1968 Jun. PMID 4876138, Free PMC Article
    5. Characteristics of the deo operon: role in thymine utilization and sensitivity to deoxyribonucleosides. Lomax MS, et al. J Bacteriol, 1968 Aug. PMID 4877128, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: The internal regulated promoter of the deo operon of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables manganese ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphopentomutase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphopentomutase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphopentomutase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 2-deoxyribose 1-phosphate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in 5-phosphoribose 1-diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular metabolic compound salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within deoxyribonucleotide catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleotide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphopentomutase
    NP_418800.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4619603..4620826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418800.1 phosphopentomutase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418800.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A418GHU9
      Conserved Domains (1) summary
      PRK05362
      Location:1 → 407
      PRK05362; phosphopentomutase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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