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    rfbC dTDP-4-dehydrorhamnose 3,5-epimerase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947482, updated on 3-Dec-2024

    Summary

    Official Symbol
    rfbC
    Official Full Name
    dTDP-4-dehydrorhamnose 3,5-epimerase
    Primary source
    ECOCYC:EG11979
    Locus tag
    b2038
    See related
    ASAP:ABE-0006759
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2032; rfbD; rmlC
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    Genomic context

    Sequence:
    NC_000913.3 (2109581..2110138, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative O-antigen polymerase Neighboring gene UDP-galactopyranose mutase Neighboring gene polyisoprenol-linked O16-antigen repeat unit flippase Neighboring gene glucose-1-phosphate thymidylyltransferase 1 Neighboring gene dTDP-4-dehydrorhamnose reductase Neighboring gene dTDP-glucose 4,6-dehydratase 1 Neighboring gene UTP:glucose-1-phosphate uridylyltransferase, low activity

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables dTDP-4-dehydrorhamnose 3,5-epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables dTDP-4-dehydrorhamnose 3,5-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables dTDP-4-dehydrorhamnose 3,5-epimerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in O antigen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in dTDP-rhamnose biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dTDP-rhamnose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipopolysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipopolysaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in polysaccharide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in polysaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within response to UV IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    dTDP-4-dehydrorhamnose 3,5-epimerase
    NP_416542.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2109581..2110138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416542.1 dTDP-4-dehydrorhamnose 3,5-epimerase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416542.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P37745
      Conserved Domains (1) summary
      TIGR01221
      Location:2179
      rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase