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    pdxK pyridoxine/pyridoxal/pyridoxamine kinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946881, updated on 17-Dec-2024

    Summary

    Official Symbol
    pdxK
    Official Full Name
    pyridoxine/pyridoxal/pyridoxamine kinase
    Primary source
    ECOCYC:G7259
    Locus tag
    b2418
    See related
    ASAP:ABE-0007973
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2413; pdxL; yfeI
    Summary
    Involved in the salvage pathway of pyridoxal 5'-phosphate biosynthesis. [More information is available at EcoGene: EG12642]. The subunit structure is unknown. [More information is available at EcoCyc: G7259].
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    Genomic context

    Sequence:
    NC_000913.3 (2536386..2537237, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PTS enzyme I Neighboring gene Enzyme IIA(Glc) Neighboring gene DUF5329 domain-containing protein YfeK Neighboring gene PF05406 family protein YfeS

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydroxymethylpyrimidine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydroxymethylpyrimidine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pyridoxal kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables pyridoxal kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pyridoxal kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables pyridoxal kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables pyridoxal phosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in pyridoxal 5'-phosphate salvage IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in pyridoxal 5'-phosphate salvage IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pyridoxal 5'-phosphate salvage IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in pyridoxal 5'-phosphate salvage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in thiamine salvage IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in vitamin B6 metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    pyridoxine/pyridoxal/pyridoxamine kinase
    NP_416913.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2536386..2537237 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416913.1 pyridoxine/pyridoxal/pyridoxamine kinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416913.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAN4NUD9
      Conserved Domains (1) summary
      PRK08176
      Location:1281
      pdxK; pyridoxine/pyridoxal/pyridoxamine kinase