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    yadC fimbrial tip-adhesin YadC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944837, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yadC
    Official Full Name
    fimbrial tip-adhesin YadC
    Primary source
    ECOCYC:EG11678
    Locus tag
    b0135
    See related
    ASAP:ABE-0000470
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0134
    Summary
    One of 25 FimA homologs in EcoGene. [More information is available at EcoGene: EG11678]. YadC is a hypothetical protein. [More information is available at EcoCyc: EG11678].
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    Genomic context

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    Sequence:
    NC_000913.3 (149715..150953, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pantothenate synthetase Neighboring gene 3-methyl-2-oxobutanoate hydroxymethyltransferase Neighboring gene putative fimbrial protein YadK Neighboring gene putative fimbrial protein YadL

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fimbria-Encoding Gene yadC Has a Pleiotropic Effect on Several Biological Characteristics and Plays a Role in Avian Pathogenic Escherichia coli Pathogenicity. Verma R, et al. Infect Immun, 2016 Jan. PMID 26502907, Free PMC Article
    2. Functional analysis of Escherichia coli Yad fimbriae reveals their potential role in environmental persistence. Larsonneur F, et al. Environ Microbiol, 2016 Dec. PMID 27696649
    3. Escherichia coli genes that reduce the lethal effects of stress. Han X, et al. BMC Microbiol, 2010 Feb 4. PMID 20128927, Free PMC Article
    4. Transposition is modulated by a diverse set of host factors in Escherichia coli and is stimulated by nutritional stress. Twiss E, et al. Mol Microbiol, 2005 Sep. PMID 16135227
    5. Escherichia coli K-12 possesses multiple cryptic but functional chaperone-usher fimbriae with distinct surface specificities. Korea CG, et al. Environ Microbiol, 2010 Jul. PMID 20345943

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. YadC production participates to binding of E. coli K-12 to human eukaryotic cells.
      Title: Functional analysis of Escherichia coli Yad fimbriae reveals their potential role in environmental persistence.
    2. the results suggest that the fimbrial adhesin YadC plays a role in adhesion, internalization, and motility of the avian pathogenic Escherichia coli strain and contributes to its pathogenicity, particularly in the beginning of the infection process.
      Title: Fimbria-Encoding Gene yadC Has a Pleiotropic Effect on Several Biological Characteristics and Plays a Role in Avian Pathogenic Escherichia coli Pathogenicity.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell adhesion involved in single-species biofilm formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cell adhesion involved in single-species biofilm formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in pilus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in pilus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in pilus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fimbrial tip-adhesin YadC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      149715..150953 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414677.1 fimbrial tip-adhesin YadC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414677.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377DYP6, A0A895P4A8, A0A8T6A3U5
      Conserved Domains (1) summary
      PRK09723
      Location:1 → 412
      PRK09723; fimbrial-like adhesin
    Nucleotide Protein
    Heading Accession and Version

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