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    mhpF acetaldehyde dehydrogenase (acetylating) MhpF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945008, updated on 3-Dec-2024

    Summary

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    Official Symbol
    mhpF
    Official Full Name
    acetaldehyde dehydrogenase (acetylating) MhpF
    Primary source
    ECOCYC:M014
    Locus tag
    b0351
    See related
    ASAP:ABE-0001207
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0348
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    Genomic context

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    Sequence:
    NC_000913.3 (372921..373871)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 3-carboxyethylcatechol 2,3-dioxygenase Neighboring gene 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase Neighboring gene 2-hydroxypentadienoate hydratase Neighboring gene 4-hydroxy-2-oxovalerate aldolase Neighboring gene 3-hydroxyphenylpropionate/3-hydroxycinnamate:H(+) symporter Neighboring gene DUF2058 domain-containing protein YaiL

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Catalytic properties of a bacterial acylating acetaldehyde dehydrogenase: evidence for several active oligomeric states and coenzyme A activation upon binding. Fischer B, et al. Chem Biol Interact, 2013 Feb 25. PMID 23237860
    2. Stereospecificity in meta-fission catabolic pathways. Burlingame R, et al. J Bacteriol, 1983 Jul. PMID 6345511, Free PMC Article
    3. Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli. Lee SJ, et al. Biochem Biophys Res Commun, 2006 Aug 4. PMID 16782065
    4. Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12. Ferrández A, et al. J Bacteriol, 1997 Apr. PMID 9098055, Free PMC Article
    5. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz E, et al. J Bacteriol, 1998 Jun. PMID 9603882, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. expression of mhpE occurs only when MhpF is available for the formation of a complex
      Title: Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acetaldehyde dehydrogenase (acetylating) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables acetaldehyde dehydrogenase (acetylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 3-phenylpropionate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acetaldehyde dehydrogenase (acetylating) MhpF
    NP_414885.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      372921..373871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414885.1 acetaldehyde dehydrogenase (acetylating) MhpF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414885.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376X3M2, A0A6D0IC26
      Conserved Domains (1) summary
      PRK08300
      Location:1 → 316
      PRK08300; acetaldehyde dehydrogenase; Validated
    Nucleotide Protein
    Heading Accession and Version

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