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    lsrA Autoinducer-2 ABC transporter ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945680, updated on 17-Dec-2024

    Summary

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    Official Symbol
    lsrA
    Official Full Name
    Autoinducer-2 ABC transporter ATP binding subunit
    Primary source
    ECOCYC:G6800
    Locus tag
    b1513
    See related
    ASAP:ABE-0005056
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1506; ego; ydeX
    Summary
    LsrA is paralogous to ribose transport ATPase RbsA. [More information is available at EcoGene: EG13806]. LsrA is an ATP-binding component of a predicted ATP-dependent sugar transporter. [More information is available at EcoCyc: G6800].
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    Genomic context

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    Sequence:
    NC_000913.3 (1601490..1603025)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene autoinducer-2 kinase Neighboring gene DNA-binding transcriptional repressor LsrR Neighboring gene Autoinducer-2 ABC transporter membrane subunit LsrC Neighboring gene Autoinducer-2 ABC transporter membrane subunit LsrD Neighboring gene Autoinducer-2 ABC transporter periplasmic binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LsrR-binding site recognition and regulatory characteristics in Escherichia coli AI-2 quorum sensing. Xue T, et al. Cell Res, 2009 Nov. PMID 19636340
    2. Interference with AI-2-mediated bacterial cell-cell communication. Xavier KB, et al. Nature, 2005 Sep 29. PMID 16193054, Free PMC Article
    3. The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Taga ME, et al. Mol Microbiol, 2001 Nov. PMID 11722742
    4. Global gene expression in Escherichia coli biofilms. Schembri MA, et al. Mol Microbiol, 2003 Apr. PMID 12657059
    5. Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. Xavier KB, et al. J Bacteriol, 2005 Jan. PMID 15601708, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in autoinducer AI-2 transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in quorum sensing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Autoinducer-2 ABC transporter ATP binding subunit
    NP_416030.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1601490..1603025
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416030.1 Autoinducer-2 ABC transporter ATP binding subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416030.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376K072
      Conserved Domains (1) summary
      PRK15439
      Location:1 → 511
      PRK15439; autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
    Nucleotide Protein
    Heading Accession and Version

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