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    araF arabinose ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946409, updated on 3-Dec-2024

    Summary

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    Official Symbol
    araF
    Official Full Name
    arabinose ABC transporter periplasmic binding protein
    Primary source
    ECOCYC:EG10057
    Locus tag
    b1901
    See related
    ASAP:ABE-0006330
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1899
    Summary
    The AraFGH arabinose transporter is a member of the ATP Binding Cassette (ABC) transporter superfamily. [More information is available at EcoCyc: EG10057].
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    Genomic context

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    Sequence:
    NC_000913.3 (1985139..1986128, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene arabinose ABC transporter membrane subunit Neighboring gene arabinose ABC transporter ATP binding subunit Neighboring gene putative ferritin-like protein Neighboring gene DUF2766 domain-containing protein YecJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino acid sequence of the L-arabinose-binding protein from Escherichia coli B/r. Hogg RW, et al. J Biol Chem, 1977 Jul 25. PMID 326784
    2. Computational design of ligand binding is not a solved problem. Schreier B, et al. Proc Natl Acad Sci U S A, 2009 Nov 3. PMID 19833875, Free PMC Article
    3. Global changes in local protein dynamics reduce the entropic cost of carbohydrate binding in the arabinose-binding protein. MacRaild CA, et al. J Mol Biol, 2007 May 4. PMID 17368482, Free PMC Article
    4. The 2.8-A resolution structure of the L-arabinose-binding protein from Escherichia coli. Polypeptide chain folding, domain similarity, and probable location of sugar-binding site. Quiocho FA, et al. J Biol Chem, 1977 Jul 25. PMID 326785
    5. A Pro to Gly mutation in the hinge of the arabinose-binding protein enhances binding and alters specificity. Sugar-binding and crystallographic studies. Vermersch PS, et al. J Biol Chem, 1990 Sep 25. PMID 2204627

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ABC-type monosaccharide transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables monosaccharide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-arabinose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-arabinose transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in outer membrane-bounded periplasmic space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    arabinose ABC transporter periplasmic binding protein
    NP_416414.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1985139..1986128 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416414.1 arabinose ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416414.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5N3CW58, A0A5N8HDW1
      Conserved Domains (1) summary
      cd01540
      Location:27 → 321
      PBP1_arabinose_binding; periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily
    Nucleotide Protein
    Heading Accession and Version

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