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    nrdH glutaredoxin-like protein NrdH [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947161, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nrdH
    Official Full Name
    glutaredoxin-like protein NrdH
    Primary source
    ECOCYC:G7401
    Locus tag
    b2673
    See related
    ASAP:ABE-0008802
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2667; ygaN
    Summary
    Purified NrdH protein was N-terminally sequenced to show the initial Met is not clipped. [More information is available at EcoGene: EG13286]. NrdH is a functional hydrogen donor for ribonucleotide reductase. [More information is available at EcoCyc: G7401].
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    Genomic context

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    Sequence:
    NC_000913.3 (2800723..2800968)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2002 domain-containing protein YgaC Neighboring gene DUF883 domain-containing protein YgaM Neighboring gene dimanganese-tyrosyl radical cofactor maintenance flavodoxin NrdI Neighboring gene ribonucleoside-diphosphate reductase 2 subunit alpha Neighboring gene ribonucleoside-diphosphate reductase 2 subunit beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression analysis of the nrdHIEF operon from Escherichia coli. Conditions that trigger the transcript level in vivo. Monje-Casas F, et al. J Biol Chem, 2001 May 25. PMID 11278973
    2. Characterization of Escherichia coli NrdH. A glutaredoxin-like protein with a thioredoxin-like activity profile. Jordan A, et al. J Biol Chem, 1997 Jul 18. PMID 9218434
    3. In vivo requirement for glutaredoxins and thioredoxins in the reduction of the ribonucleotide reductases of Escherichia coli. Gon S, et al. Antioxid Redox Signal, 2006 May-Jun. PMID 16771665
    4. A method for direct cloning of fur-regulated genes: identification of seven new fur-regulated loci in Escherichia coli. Vassinova N, et al. Microbiology (Reading), 2000 Dec. PMID 11101675
    5. NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes. Torrents E, et al. J Bacteriol, 2007 Jul. PMID 17496099, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables electron transfer activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cell redox homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cell redox homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glutaredoxin-like protein NrdH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2800723..2800968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417159.1 glutaredoxin-like protein NrdH [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417159.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A418GQ56
      Conserved Domains (1) summary
      PRK10329
      Location:1 → 81
      PRK10329; glutaredoxin-like protein NrdH
    Nucleotide Protein
    Heading Accession and Version

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