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    hybB hydrogenase 2 membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948615, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hybB
    Official Full Name
    hydrogenase 2 membrane subunit
    Primary source
    ECOCYC:EG11800
    Locus tag
    b2995
    See related
    ASAP:ABE-0009830
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2989
    Summary
    The HybB protein is predicted to be an integral membrane component of hydrogenase 2 . [More information is available at EcoCyc: EG11800].
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    Genomic context

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    Sequence:
    NC_000913.3 (3142986..3144164, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase maturation protein HybF Neighboring gene hydrogenase 2-specific chaperone Neighboring gene hydrogenase 2 maturation protease Neighboring gene hydrogenase 2 large subunit Neighboring gene hydrogenase 2 iron-sulfur protein Neighboring gene hydrogenase 2 small subunit Neighboring gene DUF2623 domain-containing protein YghW

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino acid variants of the HybB membrane subunit of Escherichia coli [NiFe]-hydrogenase-2 support a role in proton transfer. Lubek D, et al. FEBS Lett, 2019 Aug. PMID 31260099
    2. Isolation and characterisation of a soluble active fragment of hydrogenase isoenzyme 2 from the membranes of anaerobically grown Escherichia coli. Ballantine SP, et al. Eur J Biochem, 1986 Apr 15. PMID 3516690
    3. Maturation of [NiFe]-hydrogenases in Escherichia coli. Forzi L, et al. Biometals, 2007 Jun. PMID 17216401
    4. The hydrogenases and formate dehydrogenases of Escherichia coli. Sawers G. Antonie Van Leeuwenhoek, 1994. PMID 7747941
    5. Co-translocation of a periplasmic enzyme complex by a hitchhiker mechanism through the bacterial tat pathway. Rodrigue A, et al. J Biol Chem, 1999 May 7. PMID 10224080

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in anaerobic electron transport chain IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within anaerobic respiration EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in anaerobic respiration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in anaerobic respiration IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of [Ni-Fe] hydrogenase complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydrogenase 2 membrane subunit
    NP_417469.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3142986..3144164 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417469.1 hydrogenase 2 membrane subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417469.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9QE14, A0A7D7EY88, A0A8T5ZFM9
      Conserved Domains (1) summary
      PRK10881
      Location:1 → 392
      PRK10881; Ni/Fe-hydrogenase cytochrome b subunit
    Nucleotide Protein
    Heading Accession and Version

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