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    agaI putative deaminase AgaI [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947985, updated on 3-Dec-2024

    Summary

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    Official Symbol
    agaI
    Official Full Name
    putative deaminase AgaI
    Primary source
    ECOCYC:G7636
    Locus tag
    b3141
    See related
    ASAP:ABE-0010317
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3129; yraG
    Summary
    Unlike other Escherichia coli strains, K-12 is unable to grow on N-acetylgalactosamine as a source of carbon and energy. [More information is available at EcoCyc: G7636].
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    Genomic context

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    Sequence:
    NC_000913.3 (3286270..3287025)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene galactosamine-specific PTS enzyme IIB component Neighboring gene galactosamine-specific PTS enzyme IIC component Neighboring gene galactosamine-specific PTS enzyme IID component Neighboring gene putative fimbrial protein YraH Neighboring gene putative fimbrial chaperone YraI

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic analysis of the roles of agaA, agaI, and agaS genes in the N-acetyl-D-galactosamine and D-galactosamine catabolic pathways in Escherichia coli strains O157:H7 and C. Hu Z, et al. BMC Microbiol, 2013 May 1. PMID 23634833, Free PMC Article
    2. An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Reed JL, et al. Genome Biol, 2003. PMID 12952533, Free PMC Article
    3. Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli. Reizer J, et al. Microbiology (Reading), 1996 Feb. PMID 8932697
    4. Pathways for the utilization of N-acetyl-galactosamine and galactosamine in Escherichia coli. Brinkkötter A, et al. Mol Microbiol, 2000 Jul. PMID 10931310
    5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The agaI, nagB, and agaI nagB mutants were not affected in Aga and D-galactosamine utilization indicating that neither agaI nor nagB is involved in the deamination and isomerization of D-galactosamine-6-P.
      Title: Genetic analysis of the roles of agaA, agaI, and agaS genes in the N-acetyl-D-galactosamine and D-galactosamine catabolic pathways in Escherichia coli strains O157:H7 and C.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables galactosamine-6-phosphate isomerase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables glucosamine-6-phosphate deaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucosamine-6-phosphate deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in N-acetylglucosamine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in N-acetylglucosamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in N-acetylneuraminate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glucosamine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative deaminase AgaI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3286270..3287025
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417610.1 putative deaminase AgaI [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417610.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7FDW0
      Conserved Domains (1) summary
      PRK09762
      Location:20 → 251
      PRK09762; galactosamine-6-phosphate isomerase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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