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    ybcN DNA base-flipping protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945162, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ybcN
    Official Full Name
    DNA base-flipping protein
    Primary source
    ECOCYC:G6303
    Locus tag
    b0547
    See related
    ASAP:ABE-0001874
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0538
    Summary
    YbcN selectively binds G:T-mismatched DNA and has base-flipping activity (Chen, 2008). [More information is available at EcoGene: EG13630]. YbcN binds to double-stranded DNA with a G:T mismatch and acts as a base-flipping protein. [More information is available at EcoCyc: G6303].
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    Genomic context

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    Sequence:
    NC_000913.3 (572466..572921)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic protein YbcL Neighboring gene putative DNA-binding transcriptional regulator Neighboring gene uncharacterized protein YlcH Neighboring gene NinE family prophage protein Neighboring gene putative nuclease YbcO Neighboring gene crossover junction endodeoxyribonuclease RusA Neighboring gene uncharacterized protein YlcG

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phage ORF family recombinases: conservation of activities and involvement of the central channel in DNA binding. Curtis FA, et al. PLoS One, 2014. PMID 25083707, Free PMC Article
    2. A proteome chip approach reveals new DNA damage recognition activities in Escherichia coli. Chen CS, et al. Nat Methods, 2008 Jan. PMID 18084297, Free PMC Article
    3. Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82. Mahdi AA, et al. J Mol Biol, 1996 Apr 5. PMID 8648624
    4. Prophages and bacterial genomics: what have we learned so far? Casjens S. Mol Microbiol, 2003 Jul. PMID 12886937
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables bubble DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA base-flipping protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      572466..572921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415079.1 DNA base-flipping protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415079.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A444R530
      Conserved Domains (1) summary
      PRK09741
      Location:5 → 151
      PRK09741; hypothetical protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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