U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pnuC nicotinamide riboside transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945350, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    pnuC
    Official Full Name
    nicotinamide riboside transporter
    Primary source
    ECOCYC:EG11700
    Locus tag
    b0751
    See related
    ASAP:ABE-0002547
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0740
    Summary
    The pnuC gene encodes a component of the Nicotinamide Mononucleotide (NMN) transport system. [More information is available at EcoCyc: EG11700].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (783166..783885)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene quinolinate synthase Neighboring gene Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter Neighboring gene PF13985 family protein YbgS Neighboring gene 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Assimilation of nicotinamide mononucleotide requires periplasmic AphA phosphatase in Salmonella enterica. Grose JH, et al. J Bacteriol, 2005 Jul. PMID 15968063, Free PMC Article
    2. Regulation of NAD metabolism in Salmonella typhimurium: genetic analysis and cloning of the nadR repressor locus. Foster JW, et al. Mol Gen Genet, 1987 Jun. PMID 3039308
    3. Pyridine nucleotide cycle of Salmonella typhimurium: in vitro demonstration of nicotinamide mononucleotide deamidase and characterization of pnuA mutants defective in nicotinamide mononucleotide transport. Kinney DM, et al. J Bacteriol, 1979 Nov. PMID 387742, Free PMC Article
    4. PnuC and the utilization of the nicotinamide riboside analog 3-aminopyridine in Haemophilus influenzae. Sauer E, et al. Antimicrob Agents Chemother, 2004 Dec. PMID 15561822, Free PMC Article
    5. Molecular biology of pyridine nucleotide biosynthesis in Escherichia coli. Cloning and characterization of quinolinate synthesis genes nadA and nadB. Flachmann R, et al. Eur J Biochem, 1988 Aug 1. PMID 2841129

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables nicotinamide riboside transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nicotinamide riboside transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within nicotinamide riboside transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in nicotinamide riboside transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    nicotinamide riboside transporter

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      783166..783885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415272.1 nicotinamide riboside transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415272.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376MAJ0
      Conserved Domains (1) summary
      PRK15397
      Location:1 → 239
      PRK15397; nicotinamide riboside transporter PnuC; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.