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    tcyL cystine ABC transporter membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949105, updated on 3-Dec-2024

    Summary

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    Official Symbol
    tcyL
    Official Full Name
    cystine ABC transporter membrane subunit
    Primary source
    ECOCYC:G7037
    Locus tag
    b1918
    See related
    ASAP:ABE-0006386
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1917; yecS
    Summary
    AFMB Structural Genomics target Number 110 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG14037]. YecS is an inner membrane protein with three predicted transmembrane domains. [More information is available at EcoCyc: G7037].
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    Genomic context

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    Sequence:
    NC_000913.3 (1997811..1998479, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator SdiA Neighboring gene ncRNA Neighboring gene cystine ABC transporter ATP binding subunit Neighboring gene D-cysteine desulfhydrase Neighboring gene cystine ABC transporter periplasmic binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bacterial transporters for sulfate and organosulfur compounds. Kertesz MA. Res Microbiol, 2001 Apr-May. PMID 11421275
    2. Physiological Roles and Adverse Effects of the Two Cystine Importers of Escherichia coli. Chonoles Imlay KR, et al. J Bacteriol, 2015 Dec. PMID 26350134, Free PMC Article
    3. Susceptibility of Escherichia coli to the toxic L-proline analogue L-selenaproline is dependent on two L-cystine transport systems. Deutch CE, et al. J Appl Microbiol, 2014 Nov. PMID 25139244
    4. Cell-free complements in vivo expression of the E. coli membrane proteome. Savage DF, et al. Protein Sci, 2007 May. PMID 17456747, Free PMC Article
    5. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Zhang N, et al. Proteomics, 2007 Feb. PMID 17309111

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-cystine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-cystine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-cystine transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-cystine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within L-cystine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within L-cystine transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cysteine transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within diaminopimelate transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within sulfur utilization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ATP-binding cassette (ABC) transporter complex RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cystine ABC transporter membrane subunit
    NP_416428.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1997811..1998479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416428.1 cystine ABC transporter membrane subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416428.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7D7PKK7, A0A8S7EJY5
      Conserved Domains (1) summary
      PRK15100
      Location:1 → 220
      PRK15100; cystine ABC transporter permease
    Nucleotide Protein
    Heading Accession and Version

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