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    gatD galactitol-1-phosphate 5-dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946598, updated on 17-Dec-2024

    Summary

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    Official Symbol
    gatD
    Official Full Name
    galactitol-1-phosphate 5-dehydrogenase
    Primary source
    ECOCYC:EG12417
    Locus tag
    b2091
    See related
    ASAP:ABE-0006924
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2084
    Summary
    Some strains of Escherichia coli K-12 are able to utilize galactitol as the sole source of carbon. [More information is available at EcoCyc: EG12417].
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    Genomic context

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    Sequence:
    NC_000913.3 (2171833..2172873, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipid kinase YegS Neighboring gene pseudo Neighboring gene IS3 element protein InsE Neighboring gene IS3 element protein InsF Neighboring gene pseudo Neighboring gene galactitol-specific PTS enzyme IIB component

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The crystal structure of galactitol-1-phosphate 5-dehydrogenase from Escherichia coli K12 provides insights into its anomalous behavior on IMAC processes. Esteban-Torres M, et al. FEBS Lett, 2012 Sep 21. PMID 22979983
    2. Enantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coli. Benavente R, et al. Acta Crystallogr D Biol Crystallogr, 2015 Jul. PMID 26143925
    3. Genotypic exclusion: a novel relationship between the ribitol-arabitol and galactitol genes of E. coli. Link CD, et al. Mol Gen Genet, 1983. PMID 6343795
    4. Mapping of mglB, the structural gene of the galactose-binding protein of Escherichia coli. Boos W, et al. Mol Gen Genet, 1981. PMID 6278261
    5. Mapping of the gene for cytidine deaminase (cdd) in Escherichia coli K-12. Josephsen J, et al. J Bacteriol, 1983 Apr. PMID 6339482, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables galactitol-1-phosphate 5-dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables galactitol-1-phosphate 5-dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables galactitol-1-phosphate 5-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within galactitol catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in galactitol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    galactitol-1-phosphate 5-dehydrogenase
    NP_416594.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2171833..2172873 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416594.1 galactitol-1-phosphate 5-dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416594.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5YFA5
      Conserved Domains (1) summary
      PRK10309
      Location:1 → 344
      PRK10309; galactitol-1-phosphate 5-dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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