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    tas putative NADP(H)-dependent aldo-keto reductase Tas [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947306, updated on 17-Dec-2024

    Summary

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    Official Symbol
    tas
    Official Full Name
    putative NADP(H)-dependent aldo-keto reductase Tas
    Primary source
    ECOCYC:G7462
    Locus tag
    b2834
    See related
    ASAP:ABE-0009298
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2830; ygdS
    Summary
    The natural substrate and physiological role for Tas is unknown. [More information is available at EcoGene: EG13093]. Tas is required for starvation-associated mutational suppression of a tyrA14(oc) allele . [More information is available at EcoCyc: G7462].
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    Genomic context

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    Sequence:
    NC_000913.3 (2971597..2972637)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF03741 family inner membrane protein YgdQ Neighboring gene DUF903 domain-containing lipoprotein YgdR Neighboring gene lysophospholipid transporter Neighboring gene fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of the Escherichia coli Tas protein, an NADP(H)-dependent aldo-keto reductase. Obmolova G, et al. Proteins, 2003 Nov 1. PMID 14517983
    2. Identification of a mutation causing increased expression of the tas gene in Escherichia coli FX-11. Johnson JM 3rd, et al. Mutat Res, 2001 Aug 8. PMID 11470487
    3. Reversion of the tyrosine ochre strain Escherichia coli WU3610 under starvation conditions depends on a new gene tas. Timms AR, et al. Genetics, 1998 Apr. PMID 9560382, Free PMC Article
    4. Protein abundance profiling of the Escherichia coli cytosol. Ishihama Y, et al. BMC Genomics, 2008 Feb 27. PMID 18304323, Free PMC Article
    5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables aldo-keto reductase (NADPH) activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables aldo-keto reductase (NADPH) activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to amino acid starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative NADP(H)-dependent aldo-keto reductase Tas

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2971597..2972637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417311.1 putative NADP(H)-dependent aldo-keto reductase Tas [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417311.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2H4TVR2
      Conserved Domains (1) summary
      PRK10625
      Location:1 → 346
      tas; putative aldo-keto reductase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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