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    exuR DNA-binding transcriptional repressor ExuR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947602, updated on 17-Dec-2024

    Summary

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    Official Symbol
    exuR
    Official Full Name
    DNA-binding transcriptional repressor ExuR
    Primary source
    ECOCYC:EG12739
    Locus tag
    b3094
    See related
    ASAP:ABE-0010176
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3085
    Summary
    ExuR is an HTH GntR-type DNA-binding transcriptional regulator. [More information is available at EcoGene: EG12739]. The Exuronate repressor," ExuR, is a DNA-binding transcription factor that negatively regulates its own synthesis and represses transcription of the operons involved in transport and catabolism of galacturonate and glucuronate . [More information is available at EcoCyc: EG12739].
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    Genomic context

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    Sequence:
    NC_000913.3 (3246652..3247428)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-glucoronate/D-galacturonate isomerase Neighboring gene hexuronate transporter Neighboring gene protein YqiM Neighboring gene DedA family protein YqjA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic analysis of uxuR and exuR genes: evidence for ExuR and UxuR monomer repressors interactions. Ritzenthaler P, et al. Mol Gen Genet, 1985. PMID 3929016
    2. Regulation and transcription direction of exuR, a self-regulated repressor in escherichia coli K-12. Hugovieux-Cotte-Pattat N, et al. J Mol Biol, 1982 Mar 25. PMID 6808145
    3. Control of hexuronate metabolism in Escherichia coli by the two interdependent regulators, ExuR and UxuR: derepression by heterodimer formation. Tutukina MN, et al. Microbiology (Reading), 2016 Jul. PMID 27129867
    4. Role of the b subunit of the Escherichia coli proton-translocating ATPase. A mutagenic analysis. Porter AC, et al. J Biol Chem, 1985 Jul 5. PMID 2861200
    5. Interchangeability of repressors for the control of the uxu and uid operons in E. coli K12. Ritzenthaler P, et al. Mol Gen Genet, 1983. PMID 6353163

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional repressor ExuR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3246652..3247428
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417565.2 DNA-binding transcriptional repressor ExuR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417565.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AQL8
      Conserved Domains (1) summary
      PRK11523
      Location:1 → 253
      PRK11523; transcriptional regulator ExuR
    Nucleotide Protein
    Heading Accession and Version

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