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    yrfG purine nucleotidase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947904, updated on 3-Dec-2024

    Summary

    Official Symbol
    yrfG
    Official Full Name
    purine nucleotidase
    Primary source
    ECOCYC:G7742
    Locus tag
    b3399
    See related
    ASAP:ABE-0011092
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3386
    Summary
    HAD superfamily. [More information is available at EcoGene: EG12928]. YrfG is a purine nucleotidase belonging to the superfamily of haloacid dehalogenase (HAD)-like hydrolases. [More information is available at EcoCyc: G7742].
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    Genomic context

    Sequence:
    NC_000913.3 (3528669..3529337)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ADP-sugar diphosphatase NudE Neighboring gene inner membrane protein IgaA Neighboring gene heat shock protein Hsp15 Neighboring gene molecular chaperone Hsp33

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 5'-nucleotidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GMP 5'-nucleotidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables IMP 5'-nucleotidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables XMP 5'-nucleosidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables manganese ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoglycolate phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables purine nucleosidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    purine nucleotidase
    NP_417858.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3528669..3529337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417858.4 purine nucleotidase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417858.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A418GBE6
      Conserved Domains (1) summary
      PRK14988
      Location:1222
      PRK14988; GMP/IMP nucleotidase; Provisional