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    rlmJ 23S rRNA m(6)A2030 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948012, updated on 17-Dec-2024

    Summary

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    Official Symbol
    rlmJ
    Official Full Name
    23S rRNA m(6)A2030 methyltransferase
    Primary source
    ECOCYC:EG12234
    Locus tag
    b3499
    See related
    ASAP:ABE-0011428
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3484; yhiR
    Summary
    yhiR is a homologue of the H. influenzae competence gene comJ. [More information is available at EcoCyc: EG12234].
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    Genomic context

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    Sequence:
    NC_000913.3 (3645385..3646227)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 16S rRNA m(2)G1516 methyltransferase Neighboring gene oligopeptidase A Neighboring gene glutathione reductase (NADPH) Neighboring gene membrane toxin DinQ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transforming DNA uptake gene orthologs do not mediate spontaneous plasmid transformation in Escherichia coli. Sun D, et al. J Bacteriol, 2009 Feb. PMID 19011021, Free PMC Article
    2. DNA as a nutrient: novel role for bacterial competence gene homologs. Finkel SE, et al. J Bacteriol, 2001 Nov. PMID 11591672, Free PMC Article
    3. The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA. Golovina AY, et al. RNA, 2012 Sep. PMID 22847818, Free PMC Article
    4. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article
    5. Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. Palchevskiy V, et al. J Bacteriol, 2006 Jun. PMID 16707682, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 23S rRNA (adenine(2030)-N(6))-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 23S rRNA (adenine(2030)-N(6))-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 23S rRNA (adenine(2030)-N(6))-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables rRNA (adenine-N6-)-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbon utilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA base methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA base methylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in rRNA base methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within rRNA base methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    23S rRNA m(6)A2030 methyltransferase
    NP_417956.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3645385..3646227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417956.1 23S rRNA m(6)A2030 methyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417956.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AMX9, A0A8S0FGP4
      Conserved Domains (1) summary
      COG2961
      Location:2 → 280
      RlmJ; 23S rRNA A2030 N6-methylase RlmJ [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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