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    setA sugar exporter SetA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944793, updated on 3-Dec-2024

    Summary

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    Official Symbol
    setA
    Official Full Name
    sugar exporter SetA
    Primary source
    ECOCYC:EG11754
    Locus tag
    b0070
    See related
    ASAP:ABE-0000257
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0072; yabM
    Summary
    Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG11754]. YabM is a probable efflux transporter for sugars such as lactose and IPTG. [More information is available at EcoCyc: EG11754].
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    Genomic context

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    Sequence:
    NC_000913.3 (77621..78799)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator SgrR Neighboring gene ncRNA Neighboring gene PtsG glucose transporter inhibitor Neighboring gene 3-isopropylmalate dehydratase subunit LeuD Neighboring gene 3-isopropylmalate dehydratase subunit LeuC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation and function of Escherichia coli sugar efflux transporter A (SetA) during glucose-phosphate stress. Sun Y, et al. J Bacteriol, 2011 Jan. PMID 20971900, Free PMC Article
    2. The identification of a new family of sugar efflux pumps in Escherichia coli. Liu JY, et al. Mol Microbiol, 1999 Mar. PMID 10209755
    3. Functional and biochemical characterization of Escherichia coli sugar efflux transporters. Liu JY, et al. J Biol Chem, 1999 Aug 13. PMID 10438463
    4. The maltodextrin system of Escherichia coli: metabolism and transport. Dippel R, et al. J Bacteriol, 2005 Dec. PMID 16321936, Free PMC Article
    5. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carbohydrate:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate:proton symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-glucose transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within D-glucose transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within carbohydrate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in carbohydrate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to glucose-phosphate stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cellular response to glucose-phosphate stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to glucose-phosphate stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lactose transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within lactose transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sugar exporter SetA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      77621..78799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_025293.1 sugar exporter SetA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_025293.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7TMZ2
      Conserved Domains (1) summary
      TIGR00899
      Location:17 → 391
      2A0120; sugar efflux transporter
    Nucleotide Protein
    Heading Accession and Version

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    Other Literature Sources
    Molecular Biology Databases
    Research Materials