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    rplF 50S ribosomal subunit protein L6 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947803, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rplF
    Official Full Name
    50S ribosomal subunit protein L6
    Primary source
    ECOCYC:EG10869
    Locus tag
    b3305
    See related
    ASAP:ABE-0010827
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3292
    Summary
    The L6 protein is a component of the 50S subunit of the ribosome. [More information is available at EcoCyc: EG10869].
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    Genomic context

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    Sequence:
    NC_000913.3 (3445607..3446140, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 30S ribosomal subunit protein S5 Neighboring gene 50S ribosomal subunit protein L18 Neighboring gene 30S ribosomal subunit protein S8 Neighboring gene 30S ribosomal subunit protein S14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of ribosomal protein L6 in assembly of functional 50S ribosomal subunit in Escherichia coli cells. Shigeno Y, et al. Biochem Biophys Res Commun, 2016 Apr 22. PMID 27003253
    2. Alteration of ribosomal protein L6 in mutants of Escherichia coli resistant to gentamicin. Buckel P, et al. Mol Gen Genet, 1977 Dec 14. PMID 342908
    3. Alteration of ribosomal protein L6 in gentamicin-resistant strains of Escherichia coli. Effects on fidelity of protein synthesis. Kühberger R, et al. Biochemistry, 1979 Jan 9. PMID 369594
    4. Ribosomal proteins S9 and L6 participate in the binding of [3H]dibekacin to E. coli ribosomes. Akiyama T, et al. J Antibiot (Tokyo), 1981 Jun. PMID 6268595
    5. Ribosomal mutation in Escherichia coli affecting membrane stability. Bosl A, et al. Mol Gen Genet, 1981. PMID 7026977

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ribosomal protein L6 has a role in assembly of functional 50S ribosomal subunit in Escherichia coli cells
      Title: Involvement of ribosomal protein L6 in assembly of functional 50S ribosomal subunit in Escherichia coli cells.
    2. N-terminus verified by Edman degradation on mature peptide
      Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables large ribosomal subunit rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in response to antibiotic IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal large subunit assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within ribosomal large subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    50S ribosomal subunit protein L6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3445607..3446140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417764.1 50S ribosomal subunit protein L6 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417764.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A418GCH8
      Conserved Domains (1) summary
      PRK05498
      Location:1 → 177
      rplF; 50S ribosomal protein L6; Validated
    Nucleotide Protein
    Heading Accession and Version

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