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    gph phosphoglycolate phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947895, updated on 17-Dec-2024

    Summary

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    Official Symbol
    gph
    Official Full Name
    phosphoglycolate phosphatase
    Primary source
    ECOCYC:EG11871
    Locus tag
    b3385
    See related
    ASAP:ABE-0011058
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3372; yhfE
    Summary
    HAD superfamily. gph is a non-essential gene. [More information is available at EcoGene: EG11871]. The gph gene encodes a haloacid dehalogenase (HAD)-like phosphatase family enzyme with 2-phosphoglycolate phosphatase activity . [More information is available at EcoCyc: EG11871].
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    Genomic context

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    Sequence:
    NC_000913.3 (3513631..3514389, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PRD domain-containing protein YhfY Neighboring gene putative DNA-binding transcriptional regulator YhfZ Neighboring gene tryptophan--tRNA ligase Neighboring gene ribulose-phosphate 3-epimerase Neighboring gene DNA adenine methyltransferase Neighboring gene cell division protein DamX

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of 2-phosphoglycolate phosphatase of Escherichia coli in metabolism of the 2-phosphoglycolate formed in DNA repair. Teresa Pellicer M, et al. J Bacteriol, 2003 Oct. PMID 13129953, Free PMC Article
    2. Fluorescence two-dimensional difference gel electrophoresis and mass spectrometry based proteomic analysis of Escherichia coli. Yan JX, et al. Proteomics, 2002 Dec. PMID 12469338
    3. The Escherichia coli proteome: past, present, and future prospects. Han MJ, et al. Microbiol Mol Biol Rev, 2006 Jun. PMID 16760308, Free PMC Article
    4. Characterization of three genes in the dam-containing operon of Escherichia coli. Lyngstadaas A, et al. Mol Gen Genet, 1995 Jun 10. PMID 7603433
    5. Multicopy suppression underpins metabolic evolvability. Patrick WM, et al. Mol Biol Evol, 2007 Dec. PMID 17884825, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chloride ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoglycolate phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoglycolate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphoglycolate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycolate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphoglycolate phosphatase
    NP_417844.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3513631..3514389 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417844.1 phosphoglycolate phosphatase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417844.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9Q9N9, A0A8S7EAW7
      Conserved Domains (1) summary
      PRK13222
      Location:2 → 244
      PRK13222; N-acetylmuramic acid 6-phosphate phosphatase MupP
    Nucleotide Protein
    Heading Accession and Version

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