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    nfi endonuclease V [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948502, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nfi
    Official Full Name
    endonuclease V
    Primary source
    ECOCYC:EG11915
    Locus tag
    b3998
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3990; yjaF
    Summary
    nfi encodes endonuclease V (EndoV) of Escherichia coli. [More information is available at EcoCyc: EG11915].
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    Genomic context

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    Sequence:
    NC_000913.3 (4198790..4199461)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA decapping hydrolase Neighboring gene uroporphyrinogen decarboxylase Neighboring gene DUF416 domain-containing protein YjaG Neighboring gene DNA-binding protein HU-alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endonuclease V protects Escherichia coli against specific mutations caused by nitrous acid. Schouten KA, et al. Mutat Res, 1999 Dec 7. PMID 10606815
    2. Endonuclease V of Escherichia coli. Gates FT 3rd, et al. J Biol Chem, 1977 Mar 10. PMID 14159
    3. On the recognition and cleavage mechanism of Escherichia coli endodeoxyribonuclease V, a possible DNA repair enzyme. Demple B, et al. J Biol Chem, 1982 Mar 25. PMID 6277916
    4. Strand-specific cleavage of mismatch-containing DNA by deoxyinosine 3'-endonuclease from Escherichia coli. Yao M, et al. J Biol Chem, 1994 Dec 16. PMID 7989304
    5. Purification and characterization of a novel deoxyinosine-specific enzyme, deoxyinosine 3' endonuclease, from Escherichia coli. Yao M, et al. J Biol Chem, 1994 Jun 10. PMID 8206931

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: nfi, the gene for endonuclease V in Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables RNA endonuclease activity, producing 5'-phosphomonoesters IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables deoxyribonuclease V activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables deoxyribonuclease V activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables deoxyribonuclease V activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endonuclease V

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4198790..4199461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418426.2 endonuclease V [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418426.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1NTY5
      Conserved Domains (1) summary
      PRK11617
      Location:1 → 223
      PRK11617; deoxyribonuclease V
    Nucleotide Protein
    Heading Accession and Version

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