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    araD L-ribulose-5-phosphate 4-epimerase AraD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945294, updated on 3-Dec-2024

    Summary

    Official Symbol
    araD
    Official Full Name
    L-ribulose-5-phosphate 4-epimerase AraD
    Primary source
    ECOCYC:EG10055
    Locus tag
    b0061
    See related
    ASAP:ABE-0000209
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0062
    Summary
    AraD is a masked class II aldolase. [More information is available at EcoGene: EG10055]. L-ribulose 5-phosphate 4-epimerase catalyzes the third step in the pathway for degradation of L-arabinose, the epimerization at the C4 carbon to form D-xylulose-5-phosphate, which enters the |FRAME: [More information is available at EcoCyc: EG10055].
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    Genomic context

    Sequence:
    NC_000913.3 (65855..66550, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA polymerase-binding ATPase and RNAP recycling factor Neighboring gene DNA polymerase II Neighboring gene L-arabinose isomerase Neighboring gene ribulokinase

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-ribulose-phosphate 4-epimerase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables L-ribulose-phosphate 4-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables aldehyde-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    L-ribulose-5-phosphate 4-epimerase AraD
    NP_414603.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      65855..66550 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414603.1 L-ribulose-5-phosphate 4-epimerase AraD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414603.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6N8NFH2
      Conserved Domains (1) summary
      PRK08193
      Location:1231
      araD; L-ribulose-5-phosphate 4-epimerase AraD