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    metN L-methionine/D-methionine ABC transporter ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944896, updated on 3-Dec-2024

    Summary

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    Official Symbol
    metN
    Official Full Name
    L-methionine/D-methionine ABC transporter ATP binding subunit
    Primary source
    ECOCYC:EG11621
    Locus tag
    b0199
    See related
    ASAP:ABE-0000671
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    abc; ECK0199; metD
    Summary
    Upregulated by GSNO in defined medium (aerobic). [More information is available at EcoGene: EG11621]. [More information is available at EcoCyc: EG11621].
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    Genomic context

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    Sequence:
    NC_000913.3 (221614..222645, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA m(6)t(6)A37 methyltransferase Neighboring gene sensor lipoprotein RcsF Neighboring gene L-methionine/D-methionine ABC transporter membrane anchored binding protein Neighboring gene L-methionine/D-methionine ABC transporter membrane subunit Neighboring gene D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase Neighboring gene 16S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation. Kadaba NS, et al. Science, 2008 Jul 11. PMID 18621668, Free PMC Article
    2. Transport and utilization of D-methionine and other methionine sources in Escherichia coli. Kadner RJ. J Bacteriol, 1977 Jan. PMID 318639, Free PMC Article
    3. Cloning and organization of the abc and mdl genes of Escherichia coli: relationship to eukaryotic multidrug resistance. Allikmets R, et al. Gene, 1993 Dec 22. PMID 7904973
    4. A distinct mechanism for the ABC transporter BtuCD-BtuF revealed by the dynamics of complex formation. Lewinson O, et al. Nat Struct Mol Biol, 2010 Mar. PMID 20173761, Free PMC Article
    5. Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli. Nobre LS, et al. Microbiology (Reading), 2009 Mar. PMID 19246752

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ABC-type D-methionine transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ABC-type D-methionine transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-methionine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-methionine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in D-methionine transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in methionine import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Gram-negative-bacterium-type cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of methionine-importing ABC transporter complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    L-methionine/D-methionine ABC transporter ATP binding subunit
    NP_414741.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      221614..222645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414741.1 L-methionine/D-methionine ABC transporter ATP binding subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414741.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5C9AHY7
      Conserved Domains (1) summary
      PRK11153
      Location:1 → 343
      metN; DL-methionine transporter ATP-binding subunit; Provisional
    Nucleotide Protein
    Heading Accession and Version

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