moeA molybdopterin molybdotransferase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: moeA
Official Full Name: molybdopterin molybdotransferase
Primary source: ECOCYC:EG10153
Locus tag: b0827
See related: ASAP:ABE-0002823
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: bisB; chlE; ECK0817; narE
Summary: Human gephyrin resembles a fused MoeA and Mog. [More information is available at EcoGene: EG10153]. Molybdenum and tungsten cofactors of all enzymes, with the exception of nitrogenase, that require one or the other of the other for activity are present in an oxidized state as molybdate or tungstate ions that are chelated by the cis-dithiolene moiety of a molybdenum cofactor. [More information is available at EcoCyc: EG10153].
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Two different functional areas were assigned to regions at or near the MoeA active site cleft
Title: Mutational analysis of Escherichia coli MoeA: two functional activities map to the active site cleft.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molybdopterin molybdotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables molybdopterin molybdotransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables molybdopterin molybdotransferase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in Mo-molybdopterin cofactor biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within Mo-molybdopterin cofactor biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in Mo-molybdopterin cofactor biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within Mo-molybdopterin cofactor biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

NP_415348.1

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The following sections contain reference sequences that belong to a specific genome build. Explain