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    ybjG undecaprenyl pyrophosphate phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945450, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ybjG
    Official Full Name
    undecaprenyl pyrophosphate phosphatase
    Primary source
    ECOCYC:G6439
    Locus tag
    b0841
    See related
    ASAP:ABE-0002865
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0831
    Summary
    The ybjG gene is not essential, but UppP activity is essential to synthesize undecaprenyl phosphate, a C55 lipid carrier for cell wall synthesis, so a ybjG pgpB bacA triple mutant is lethal; overexpression, but not wildtype levels, of the LpxT(YeiU) UppP activity rescues the triple mutant (El Ghachi, 2005). [More information is available at EcoGene: EG13676]. YbjG is similar to a bacitracin resistance protein BcrC of Bacillus licheniformis. [More information is available at EcoCyc: G6439].
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    Genomic context

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    Sequence:
    NC_000913.3 (882792..883388, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-alanyl-D-alanine carboxypeptidase DacC Neighboring gene DNA-binding transcriptional repressor DeoR Neighboring gene multidrug efflux pump MdfA/Na(+):H(+) antiporter/K(+):H(+) antiporter Neighboring gene uncharacterized protein YbjH

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Resistance to bacitracin as modulated by an Escherichia coli homologue of the bacitracin ABC transporter BcrC subunit from Bacillus licheniformis. Harel YM, et al. J Bacteriol, 1999 Oct. PMID 10498733, Free PMC Article
    2. Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate. Touzé T, et al. Mol Microbiol, 2008 Jan. PMID 18047581, Free PMC Article
    3. An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling. Tatar LD, et al. Microbiology (Reading), 2007 Aug. PMID 17660416
    4. Unique stress response to the lactoperoxidase-thiocyanate enzyme system in Escherichia coli. Sermon J, et al. Res Microbiol, 2005 Mar. PMID 15748988
    5. Signal transduction cascade between EvgA/EvgS and PhoP/PhoQ two-component systems of Escherichia coli. Eguchi Y, et al. J Bacteriol, 2004 May. PMID 15126461, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables undecaprenyl-diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables undecaprenyl-diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peptidoglycan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to antibiotic IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    undecaprenyl pyrophosphate phosphatase
    NP_415362.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      882792..883388 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415362.1 undecaprenyl pyrophosphate phosphatase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415362.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      H9DVC7
      Conserved Domains (1) summary
      PRK11837
      Location:1 → 198
      PRK11837; undecaprenyl pyrophosphate phosphatase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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