U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    potD spermidine preferential ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945682, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    potD
    Official Full Name
    spermidine preferential ABC transporter periplasmic binding protein
    Primary source
    ECOCYC:EG10752
    Locus tag
    b1123
    See related
    ASAP:ABE-0003789
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1109
    Summary
    PotBCAD spermidine/putrescine ABC transport system. [More information is available at EcoGene: EG10752]. PotABCD is an ATP-dependent polyamine transporter that is a member of the ATP-Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10752].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1181783..1182829, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene CobB-S;protein-lysine deacetylase/desuccinylase/lipoamidase Neighboring gene putative inner membrane protein YcfZ Neighboring gene putative inner membrane protein YmfA Neighboring gene spermidine preferential ABC transporter membrane subunit PotC Neighboring gene spermidine preferential ABC transporter membrane subunit PotB Neighboring gene spermidine preferential ABC transporter ATP binding subunit

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Effect of Spermidine on Biofilm Formation in Escherichia coli K-12. Thongbhubate K, et al. J Bacteriol, 2021 Apr 21. PMID 33685971, Free PMC Article
    2. PotD protein stimulates biofilm formation by Escherichia coli. Zhang X, et al. Biotechnol Lett, 2013 Jul. PMID 23539287
    3. Prediction of the structural similarity between spermidine/putrescine-binding protein and maltose-binding protein. Matsuo Y, et al. FEBS Lett, 1994 May 23. PMID 8194593
    4. Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli. Sugiyama S, et al. J Biol Chem, 1996 Apr 19. PMID 8621624
    5. Spermidine-preferential uptake system in Escherichia coli. Identification of amino acids involved in polyamine binding in PotD protein. Kashiwagi K, et al. J Biol Chem, 1996 May 24. PMID 8647815

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Effect of Spermidine on Biofilm Formation in Escherichia coli K-12.
      Title: Effect of Spermidine on Biofilm Formation in Escherichia coli K-12.
    2. Thus, PotD is likely to change the rate of polyamine synthesis, which stimulates the expression of SOS genes and biofilm formation.
      Title: PotD protein stimulates biofilm formation by Escherichia coli.
    3. amino acid residues in PotB and PotC are involved in spermidine uptake activity, and spermidine passage from PotD to the cytoplasm is coupled to the ATPase activity of PotA through a structural change of PotA by its ATPase activity
      Title: Identification and functions of amino acid residues in PotB and PotC involved in spermidine uptake activity.
    4. Transport proteins PotD and Crr of Escherichia coli, novel fusion partners for heterologous protein expression.
      Title: Transport proteins PotD and Crr of Escherichia coli, novel fusion partners for heterologous protein expression.
    5. N-terminus verified by Edman degradation on mature peptide
      Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables polyamine binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables putrescine binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables spermidine binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables spermidine binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in polyamine transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within putrescine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in putrescine transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in spermidine transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within spermidine transport EXP
    Inferred from Experiment
    more info
    		 PubMed 
    acts_upstream_of_or_within spermidine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within spermidine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    spermidine preferential ABC transporter periplasmic binding protein
    NP_415641.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1181783..1182829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415641.1 spermidine preferential ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415641.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7CLF8
      Conserved Domains (1) summary
      PRK09501
      Location:1 → 348
      potD; spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.