U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ydbK putative pyruvate-flavodoxin oxidoreductase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946587, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ydbK
    Official Full Name
    putative pyruvate-flavodoxin oxidoreductase
    Primary source
    ECOCYC:G6701
    Locus tag
    b1378
    See related
    ASAP:ABE-0004613
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1374; pfo
    Summary
    ydbK is SoxS-regulated in Salmonella. ydbK is a nifJ-like gene, with a probable iron-sulfur center. [More information is available at EcoGene: EG13183]. Based on sequence similarity, YdbK is predicted to be a pyruvate synthase . [More information is available at EcoCyc: G6701].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1437260..1440784, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene outer membrane porin N Neighboring gene ncRNA Neighboring gene DUF333 domain-containing protein YdbJ Neighboring gene lipoprotein implicated in Novobiocin resistance Neighboring gene D-lactate dehydrogenase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Escherichia coli pyruvate:flavodoxin oxidoreductase, YdbK - regulation of expression and biological roles in protection against oxidative stress. Nakayama T, et al. Genes Genet Syst, 2013. PMID 24025246
    2. SoxS-dependent coregulation of ompN and ydbK in a multidrug-resistant Escherichia coli strain. Fàbrega A, et al. FEMS Microbiol Lett, 2012 Jul. PMID 22515487
    3. Construction of a synthetic YdbK-dependent pyruvate:H2 pathway in Escherichia coli BL21(DE3). Akhtar MK, et al. Metab Eng, 2009 May. PMID 19558967
    4. Isolation and characterization of Escherichia coli strains containing new gene fusions (soi::lacZ) inducible by superoxide radicals. Mito S, et al. J Bacteriol, 1993 May. PMID 8386722, Free PMC Article
    5. The ldhA gene encoding the fermentative lactate dehydrogenase of Escherichia coli. Bunch PK, et al. Microbiology (Reading), 1997 Jan. PMID 9025293

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the aldehyde or oxo group of donors IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyruvate-flavodoxin oxidoreductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyruvate-flavodoxin oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in electron transport chain IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to oxidative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    putative pyruvate-flavodoxin oxidoreductase

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1437260..1440784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415896.1 putative pyruvate-flavodoxin oxidoreductase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415896.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EA23
      Conserved Domains (1) summary
      TIGR02176
      Location:1 → 1166
      pyruv_ox_red; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.