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    glpA anaerobic glycerol-3-phosphate dehydrogenase subunit A [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946713, updated on 3-Dec-2024

    Summary

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    Official Symbol
    glpA
    Official Full Name
    anaerobic glycerol-3-phosphate dehydrogenase subunit A
    Primary source
    ECOCYC:EG10391
    Locus tag
    b2241
    See related
    ASAP:ABE-0007422
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2233
    Summary
    The GlpABC enzyme is loosely associated with the cell membrane. [More information is available at EcoCyc: EG10391].
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    Genomic context

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    Sequence:
    NC_000913.3 (2352647..2354275)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene glycerophosphoryl diester phosphodiesterase GlpQ Neighboring gene sn-glycerol 3-phosphate:phosphate antiporter Neighboring gene anaerobic glycerol-3-phosphate dehydrogenase subunit B Neighboring gene anaerobic glycerol-3-phosphate dehydrogenase subunit C Neighboring gene inactive recombination-promoting nuclease-like protein RpnE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Resolution of glpA and glpT loci into separate operons in Escherichia coli K-12 strains. Miki K, et al. J Bacteriol, 1979 Apr. PMID 374371, Free PMC Article
    2. Anaerobic L- -glycerophosphate dehydrogenase of Escherichia coli: its genetic locus and its physiological role. Kistler WS, et al. J Bacteriol, 1971 Dec. PMID 4945192, Free PMC Article
    3. Identification of the glpT-encoded sn-glycerol-3-phosphate permease of Escherichia coli, an oligomeric integral membrane protein. Larson TJ, et al. J Bacteriol, 1982 Dec. PMID 6754693, Free PMC Article
    4. Multiple regulatory elements for the glpA operon encoding anaerobic glycerol-3-phosphate dehydrogenase and the glpD operon encoding aerobic glycerol-3-phosphate dehydrogenase in Escherichia coli: further characterization of respiratory control. Iuchi S, et al. J Bacteriol, 1990 Jan. PMID 2403539, Free PMC Article
    5. Enzyme complex which couples glycerol-3-phosphate dehydrogenation to fumarate reduction in Escherichia coli. Miki K, et al. J Bacteriol, 1973 May. PMID 4574699, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Nucleotide sequence and gene-polypeptide relationships of the glpABC operon encoding the anaerobic sn-glycerol-3-phosphate dehydrogenase of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables glycerol-3-phosphate dehydrogenase (quinone) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycerol-3-phosphate dehydrogenase (quinone) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glycerol-3-phosphate dehydrogenase (quinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycerol-3-phosphate dehydrogenase (quinone) activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within anaerobic respiration IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in anaerobic respiration NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in glycerol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycerol-3-phosphate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within glycerol-3-phosphate catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glycerol-3-phosphate catabolic process NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in glycerol-3-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in organophosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphate-containing compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in polyol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of glycerol-3-phosphate dehydrogenase (FAD) complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of glycerol-3-phosphate dehydrogenase (FAD) complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    anaerobic glycerol-3-phosphate dehydrogenase subunit A
    NP_416744.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2352647..2354275
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416744.1 anaerobic glycerol-3-phosphate dehydrogenase subunit A [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416744.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1PX83, A0A8S7EDC4
      Conserved Domains (1) summary
      PRK11101
      Location:25 → 536
      glpA; anaerobic glycerol-3-phosphate dehydrogenase subunit A
    Nucleotide Protein
    Heading Accession and Version

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